6-Benzyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-amine

Base Information

• Chemical Name: 6-Benzyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-amine
• CAS No.: 214699-26-0
• Molecular Formula: C15H17N3
• Molecular Weight: 239.32
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID50446898
• Nikkaji Number: J1.584.618F
• Wikidata: Q72506516
• Mol file: 214699-26-0.mol

Synonyms:214699-26-0;6-Benzyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-amine;6-benzyl-7,8-dihydro-5H-1,6-naphthyridin-3-amine;3-Amino-6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine;1,6-Naphthyridin-3-amine, 5,6,7,8-tetrahydro-6-(phenylmethyl)-;5,6,7,8-TETRAHYDRO-6-(PHEHYLMETHYL)-1,6-NAPHTHYRIDIN-3-AMINE;SCHEMBL6772037;DTXSID50446898;LZCBWYQNYNKFFL-UHFFFAOYSA-N;BCP19285;MFCD09025775;SC2651;AKOS015854929;DS-10917;CS-0060533;FT-0649800;A815399;W-206632;3-Amino-6-benzyl-5,6,7,8-tetrahydro[1,6]naphthyridine;6-(phenylmethyl)-7,8-dihydro-5H-1,6-naphthyridin-3-amine;6-Benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-3-amine

Chemical Property of 6-Benzyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-amine

Chemical Property:

• Vapor Pressure: 2.53E-07mmHg at 25°C
• Refractive Index: 1.651
• Boiling Point: 421.8 °C at 760 mmHg
• PKA: 6?+-.0.20(Predicted)
• Flash Point: 208.9 °C
• PSA: 42.15000
• Density: 1.189 g/cm³
• LogP: 2.74120
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 239.142247555
• Heavy Atom Count: 18
• Complexity: 263

Purity/Quality:

97% ^*data from raw suppliers

6-Benzyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(CC2=C1N=CC(=C2)N)CC3=CC=CC=C3

Technology Process of 6-Benzyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-amine

There total 4 articles about 6-Benzyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 3-Amino-6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine (214699-26-0)

Guidance literature:

Reference yield: 39.0%

6-benzyl-3-nitro-5,6,7,8-tetrahydro[1,6]naphthyridine (214699-24-8) → 3-Amino-6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine (214699-26-0) + 6-benzyl-3-hydroxylamino-5,6,7,8-tetrahydro[1,6]naphthyridine

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In ethanol; at 50 ℃; for 0.166667h;

DOI:10.1081/SCC-100103271

Reference yield:

6-benzyl-3-nitro-5,6,7,8-tetrahydro[1,6]naphthyridine (214699-24-8) → 3-Amino-6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine (214699-26-0)

Guidance literature:

With Pd/C; hydrogen; In methanol;

DOI:10.1016/j.tetlet.2008.08.083

upstream raw materials:

6-benzyl-3-nitro-5,6,7,8-tetrahydro[1,6]naphthyridine

1-phenylmethyl-4-piperidone

Downstream raw materials:

C₁₅H₁₆N₂O