2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5⁽⁶⁾-(4-acetyl-1-piperazinyl)benzimidazole

Base Information

• Chemical Name: 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5⁽⁶⁾-(4-acetyl-1-piperazinyl)benzimidazole
• CAS No.: 120423-36-1
• Molecular Formula: C₂₇H₃₆N₄O₂
• Molecular Weight: 448.608

Synonyms:2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5⁽⁶⁾-(4-acetyl-1-piperazinyl)benzimidazole

Chemical Property of 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5⁽⁶⁾-(4-acetyl-1-piperazinyl)benzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5⁽⁶⁾-(4-acetyl-1-piperazinyl)benzimidazole

There total 1 articles about 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5⁽⁶⁾-(4-acetyl-1-piperazinyl)benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-di-tert-butyl-4-cyanophenol (1988-88-1) → 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5(6)-(4-acetyl-1-piperazinyl)benzimidazole (120423-36-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 3.8 g / HCl / 48 h / 20 °C

2: 75 percent / acetic acid / 2 h / Heating

With hydrogenchloride; In acetic acid;

Reference yield: 92.0%

2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5(6)-(4-acetyl-1-piperazinyl)benzimidazole (120423-36-1) → 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5(6)-(1-piperazinyl)benzimidazole (136415-14-0)

Guidance literature:

With hydrogenchloride; In isopropyl alcohol; for 2h; Heating;

upstream raw materials:

2,6-di-tert-butyl-4-cyanophenol

Downstream raw materials:

2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5⁽⁶⁾-(1-piperazinyl)benzimidazole

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