6-Methyl-3-azabicyclo[4.1.0]heptan-4-one

Base Information

Chemical Name:6-Methyl-3-azabicyclo[4.1.0]heptan-4-one
CAS No.:214479-62-6
Molecular Formula:C₇H₁₁NO
Molecular Weight:125.17
Hs Code.:
DSSTox Substance ID:DTXSID30472716
Mol file:214479-62-6.mol

Synonyms:214479-62-6;6-METHYL-3-AZABICYCLO[4.1.0]HEPTAN-4-ONE;3-Azabicyclo[4.1.0]heptan-4-one,6-methyl-(9CI);SCHEMBL7788279;DTXSID30472716;AKOS006356855

Suppliers and Price of 6-Methyl-3-azabicyclo[4.1.0]heptan-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 6-Methyl-3-azabicyclo[4.1.0]heptan-4-one

Chemical Property:

PSA：32.59000
LogP:0.80840
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:125.084063974
Heavy Atom Count:9
Complexity:166

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CC1CNC(=O)C2

Technology Process of 6-Methyl-3-azabicyclo[4.1.0]heptan-4-one

There total 3 articles about 6-Methyl-3-azabicyclo[4.1.0]heptan-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 20967-57-1
4-methyl-3,6-dihydropyridin-2-one

: 75-11-6
diiodomethane

: 214479-62-6
6-methyl-3-azabicyclo[4.1.0]heptan-4-one

Guidance literature:: With trimethylaluminum; In hexane; dichloromethane; at 0 - 20 ℃;
DOI:10.1016/S0223-5234(03)00017-5

Reference yield:

: 20967-57-1
4-methyl-3,6-dihydropyridin-2-one

: 75-11-6
diiodomethane

: 75-24-1
trimethylaluminum

: 214479-62-6
6-methyl-3-azabicyclo[4.1.0]heptan-4-one

Guidance literature:: With sodium hydroxide; 3-chloro-benzenecarboperoxoic acid; sodium fluoride; In hexane; dichloromethane; water; ethyl acetate;

Reference yield:

: 13466-41-6,91914-05-5
2-hydroksy-4-methyl-pyridine

: 214479-62-6
6-methyl-3-azabicyclo[4.1.0]heptan-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / Li; liquid NH₃ / tetrahydrofuran; ethanol / 1.5 h / -78 °C

2: 35 percent / AlMe₃ / CH₂Cl₂; hexane / 0 - 20 °C

With ammonia; trimethylaluminum; lithium; In tetrahydrofuran; ethanol; hexane; dichloromethane; 1: Birch reduction / 2: Simmons-Smith reaction;
DOI:10.1016/S0223-5234(03)00017-5