Toluene-4-sulfonic acid 2-{2-[3-(2-hydroxy-ethoxy)-naphthalen-2-yloxy]-ethoxy}-phenyl ester

Base Information

• Chemical Name: Toluene-4-sulfonic acid 2-{2-[3-(2-hydroxy-ethoxy)-naphthalen-2-yloxy]-ethoxy}-phenyl ester
• CAS No.: 195731-53-4
• Molecular Formula: C₂₇H₂₆O₇S
• Molecular Weight: 494.565
• Mol file: 195731-53-4.mol

Synonyms:Toluene-4-sulfonic acid 2-{2-[3-(2-hydroxy-ethoxy)-naphthalen-2-yloxy]-ethoxy}-phenyl ester

Chemical Property of Toluene-4-sulfonic acid 2-{2-[3-(2-hydroxy-ethoxy)-naphthalen-2-yloxy]-ethoxy}-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of Toluene-4-sulfonic acid 2-{2-[3-(2-hydroxy-ethoxy)-naphthalen-2-yloxy]-ethoxy}-phenyl ester

There total 2 articles about Toluene-4-sulfonic acid 2-{2-[3-(2-hydroxy-ethoxy)-naphthalen-2-yloxy]-ethoxy}-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-(2-hydroxyethoxy)phenol ditosylate (91300-54-8) + 3-(2-hydroxyethoxy) naphthalene-2-ol (195731-51-2) → Toluene-4-sulfonic acid 2-{2-[3-(2-hydroxy-ethoxy)-naphthalen-2-yloxy]-ethoxy}-phenyl ester (195731-53-4)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 80 ℃; for 20h;

DOI:10.1246/bcsj.70.1961

Reference yield:

2,3-naphthalenediol (92-44-4) → Toluene-4-sulfonic acid 2-{2-[3-(2-hydroxy-ethoxy)-naphthalen-2-yloxy]-ethoxy}-phenyl ester (195731-53-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / Bu₄NI / 3 h / 170 °C

2: 78 percent / NaH / dimethylformamide / 20 h / 80 °C

With tetra-(n-butyl)ammonium iodide; sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1246/bcsj.70.1961

Reference yield: 78.0%

Toluene-4-sulfonic acid 2-{2-[3-(2-hydroxy-ethoxy)-naphthalen-2-yloxy]-ethoxy}-phenyl ester (195731-53-4) → 2-{3-[2-(2-hydroxyphenoxy)ethoxy]-2-naphthyloxy}ethanol (195731-54-5)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; ethanol; for 3h; Heating;

DOI:10.1246/bcsj.70.1961

upstream raw materials:

2-(2-hydroxyethoxy)phenol ditosylate

3-(2-hydroxyethoxy) naphthalene-2-ol

2,3-naphthalenediol

Downstream raw materials:

2-{3-[2-(2-hydroxyphenoxy)ethoxy]-2-naphthyloxy}ethanol