Technology Process of 2-(4'-methylbiphenyl-2-yl)-1-(benzenesulfonyl)acrylonitrile
There total 11 articles about 2-(4'-methylbiphenyl-2-yl)-1-(benzenesulfonyl)acrylonitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
piperidine;
In
N,N-dimethyl-formamide; benzene;
for 18h;
Heating;
DOI:10.1021/jm00112a031
- Guidance literature:
-
Multi-step reaction with 6 steps
1: tetrahydrofuran / 2 h / 20 °C
2: 88 percent / 4.5 N aq. HCl / 12 h / Heating
3: 1.) acetyl chloride / 1.) 0 deg C, 0.25 h, 2.) reflux, 4 h
4: 42.55 g / diisobutylaluminum hydride / toluene / 0.25 h / -78 - -70 °C
5: pyridinium chlorochromate / CH2Cl2 / 0.5 h / 25 °C
6: 90 percent / piperidine / dimethylformamide; benzene / 18 h / Heating
With
piperidine; hydrogenchloride; diisobutylaluminium hydride; acetyl chloride; pyridinium chlorochromate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; benzene;
DOI:10.1021/jm00112a031
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 11 percent / Cu / 1 h / 210 °C
2: 42.55 g / diisobutylaluminum hydride / toluene / 0.25 h / -78 - -70 °C
3: pyridinium chlorochromate / CH2Cl2 / 0.5 h / 25 °C
4: 90 percent / piperidine / dimethylformamide; benzene / 18 h / Heating
With
piperidine; copper; diisobutylaluminium hydride; pyridinium chlorochromate;
In
dichloromethane; N,N-dimethyl-formamide; toluene; benzene;
DOI:10.1021/jm00112a031
