YIC-C8-434

Base Information

• Chemical Name: YIC-C8-434
• CAS No.: 214265-97-1
• Molecular Formula: C₃₁H₄₄N₂O₄
• Molecular Weight: 508.701
• Mol file: 214265-97-1.mol

Synonyms:Piperazine,1-[(2E)-3-[3,5-dimethoxy-4-(octyloxy)phenyl]-1-oxo-2-propenyl]-4-(3,4-dimethylphenyl)-(9CI); YIC-C 8-434

Chemical Property of YIC-C8-434

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 103.6-105.2 °C
• Refractive Index: 1.557
• Boiling Point: 693.902°C at 760 mmHg
• Flash Point: 373.459°C
• PSA: 51.24000
• Density: 1.076g/cm³
• LogP: 6.42480
• Solubility.: DMSO: >8 mg/mL

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of YIC-C8-434

There total 3 articles about YIC-C8-434 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.5%

N-(3,5-dimethoxy-4-hydroxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine (214266-78-1) → N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine (214265-97-1)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 96h;

DOI:10.1248/cpb.49.830

Reference yield:

trans-3,5-dimethoxy-4-hydroxycinnamic acid (530-59-6,7362-37-0) → N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine (214265-97-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 46 percent / EDC / CHCl₃ / 20 °C

2: 49.5 percent / NaH / dimethylformamide / 96 h / 20 °C

With sodium hydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In chloroform; N,N-dimethyl-formamide;

DOI:10.1248/cpb.49.830

Reference yield:

1-(3,4-dimethylphenyl)piperazine (1014-05-7) → N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine (214265-97-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 46 percent / EDC / CHCl₃ / 20 °C

2: 49.5 percent / NaH / dimethylformamide / 96 h / 20 °C

With sodium hydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In chloroform; N,N-dimethyl-formamide;

DOI:10.1248/cpb.49.830

upstream raw materials:

N-(3,5-dimethoxy-4-hydroxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine

trans-3,5-dimethoxy-4-hydroxycinnamic acid

1-(3,4-dimethylphenyl)piperazine