(E)-ethyl N-3-cyano-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-chromen-2-ylformimidate

Base Information

• Chemical Name: (E)-ethyl N-3-cyano-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-chromen-2-ylformimidate
• CAS No.: 1247933-37-4
• Molecular Formula: C₂₅H₂₂N₂O₃
• Molecular Weight: 398.461
• Mol file: 1247933-37-4.mol

Synonyms:(E)-ethyl N-3-cyano-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-chromen-2-ylformimidate

Chemical Property of (E)-ethyl N-3-cyano-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-chromen-2-ylformimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-ethyl N-3-cyano-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-chromen-2-ylformimidate

There total 1 articles about (E)-ethyl N-3-cyano-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-chromen-2-ylformimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2‐amino‐5‐oxo‐4,7‐diphenyl‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitrile (107753-02-6) + orthoformic acid triethyl ester (122-51-0) → (E)-ethyl N-3-cyano-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-chromen-2-ylformimidate (1247933-37-4)

Guidance literature:

In acetic anhydride; at 150 ℃; for 3.5h; Inert atmosphere;

DOI:10.1021/jm1009154

Reference yield: 100.0%

(E)-ethyl N-3-cyano-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-chromen-2-ylformimidate (1247933-37-4) → 2‐amino‐5‐oxo‐4,7‐diphenyl‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitrile (107753-02-6)

Guidance literature:

With formic acid; In ethanol; at 20 - 60 ℃; for 48h;

DOI:10.1021/jm1009154

Reference yield: 34.0%

(E)-ethyl N-3-cyano-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-chromen-2-ylformimidate (1247933-37-4) → C23H22N2O2

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 3h;

DOI:10.1021/jm1009154

upstream raw materials:

2‐amino‐5‐oxo‐4,7‐diphenyl‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitrile

orthoformic acid triethyl ester

Downstream raw materials:

2‐amino‐5‐oxo‐4,7‐diphenyl‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitrile