Technology Process of O-Benzoylpaniculatin
There total 21 articles about O-Benzoylpaniculatin which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 20 steps
1.1: CuI
2.1: NaI; mCPBA
3.1: 82 percent / Bu3SnH; AIBN / benzene / Heating
4.1: Li; NH3
5.1: TBAF
5.2: KHCO3; H2O2 / methanol
6.1: 95 percent / imidazole
7.1: 90 percent / PCC
8.1: 88 percent / L-Selectride
9.1: 87 percent / KH / tetrahydrofuran
10.1: 82 percent / CF3COOH
11.1: SeO2 / dioxane
13.1: LiClO4 / diethyl ether / 20 °C
14.1: aq. AcOH / tetrahydrofuran
15.1: 86 percent
16.1: (COCl)2
18.1: K2CO3 / xylene / Heating
19.1: LiAlH4 / tetrahydrofuran
With
1H-imidazole; copper(l) iodide; lithium aluminium tetrahydride; selenium(IV) oxide; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; ammonia; tri-n-butyl-tin hydride; lithium perchlorate; lithium; potassium hydride; L-Selectride; potassium carbonate; acetic acid; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; trifluoroacetic acid; sodium iodide;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; xylene; benzene;
1.1: addition; silylation / 2.1: Iodination / 3.1: Cyclization / 4.1: Reduction / 5.1: Substitution / 5.2: Oxidation / 6.1: silylation / 7.1: Oxidation / 8.1: Reduction / 9.1: benzylation / 10.1: desilylation / 11.1: allylic oxidation / 12.1: Swern oxidation / 13.1: Addition / 14.1: desilylation / 15.1: Jones oxidation / 16.1: Chlorination / 17.1: Substitution / 18.1: Cyclization / 19.1: Reduction / 20.1: Swern oxidation;
DOI:10.1021/ja992315o
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![(2S,5aR,7R,9R,9aS)-2-Hydroxymethyl-7-methyl-3-trimethylsilanyl-2,4,5,5a,6,7,8,9-octahydro-1H-cyclopenta[c]inden-9-ol](/Databaselist/images/loading.webp)
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251650-95-0
(2S,5aR,7R,9R,9aS)-2-Hydroxymethyl-7-methyl-3-trimethylsilanyl-2,4,5,5a,6,7,8,9-octahydro-1H-cyclopenta[c]inden-9-ol
- Guidance literature:
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Multi-step reaction with 15 steps
1: 95 percent / imidazole
2: 90 percent / PCC
3: 88 percent / L-Selectride
4: 87 percent / KH / tetrahydrofuran
5: 82 percent / CF3COOH
6: SeO2 / dioxane
8: LiClO4 / diethyl ether / 20 °C
9: aq. AcOH / tetrahydrofuran
10: 86 percent
11: (COCl)2
13: K2CO3 / xylene / Heating
14: LiAlH4 / tetrahydrofuran
With
1H-imidazole; lithium aluminium tetrahydride; selenium(IV) oxide; oxalyl dichloride; lithium perchlorate; potassium hydride; L-Selectride; potassium carbonate; acetic acid; pyridinium chlorochromate; trifluoroacetic acid;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; xylene;
1: silylation / 2: Oxidation / 3: Reduction / 4: benzylation / 5: desilylation / 6: allylic oxidation / 7: Swern oxidation / 8: Addition / 9: desilylation / 10: Jones oxidation / 11: Chlorination / 12: Substitution / 13: Cyclization / 14: Reduction / 15: Swern oxidation;
DOI:10.1021/ja992315o
- Guidance literature:
-
Multi-step reaction with 10 steps
1: SeO2 / dioxane
3: LiClO4 / diethyl ether / 20 °C
4: aq. AcOH / tetrahydrofuran
5: 86 percent
6: (COCl)2
8: K2CO3 / xylene / Heating
9: LiAlH4 / tetrahydrofuran
With
lithium aluminium tetrahydride; selenium(IV) oxide; oxalyl dichloride; lithium perchlorate; potassium carbonate; acetic acid;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; xylene;
1: allylic oxidation / 2: Swern oxidation / 3: Addition / 4: desilylation / 5: Jones oxidation / 6: Chlorination / 7: Substitution / 8: Cyclization / 9: Reduction / 10: Swern oxidation;
DOI:10.1021/ja992315o
