1-Chloro-3-(trimethoxysilyl)benzene

Base Information

• Chemical Name: 1-Chloro-3-(trimethoxysilyl)benzene
• CAS No.: 53883-60-6
• Molecular Formula: C₉H₁₃ClO₃Si
• Molecular Weight: 232.739
• DSSTox Substance ID: DTXSID401292614
• Mol file: 53883-60-6.mol

Synonyms:1-Chloro-3-(trimethoxysilyl)benzene;53883-60-6;DTXSID401292614

Chemical Property of 1-Chloro-3-(trimethoxysilyl)benzene

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 232.0322485
• Heavy Atom Count: 14
• Complexity: 167

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CO[Si](C1=CC(=CC=C1)Cl)(OC)OC

Technology Process of 1-Chloro-3-(trimethoxysilyl)benzene

There total 1 articles about 1-Chloro-3-(trimethoxysilyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (3-chlorophenyl)trimethoxysilane (53883-60-6)

Guidance literature:

/BRN= 937131/, CH3ONa;

Reference yield: 86.0%

(3-chlorophenyl)trimethoxysilane (53883-60-6) + tert-butyl 2-diazo-2-phenylacetate (72410-67-4) → tert-butyl 2-(3-chlorophenyl)-2-phenylacetate

Guidance literature:

With [Rh(OH)(cod)]2; tetrabutyl ammonium fluoride; tricyclohexylphosphine tetrafluoroborate; In tetrahydrofuran; water; at 80 ℃; for 5h; Inert atmosphere;

DOI:10.1021/acs.orglett.5b00052

Reference yield: 82.0%

(3-chlorophenyl)trimethoxysilane (53883-60-6) + 2-bromo-N-(3,4-dimethoxyphenyl)-2,2-difluoroacetamide → 3-chloro-N-(3,4-dimethoxyphenyl)benzamide (362722-22-3)

Guidance literature:

With potassium fluoride; 5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene; copper(ll) bromide; magnesium chloride; for 8h; Inert atmosphere; Heating;

DOI:10.3390/molecules26102957

Downstream raw materials:

1-(3-chloro-phenyl)-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undecane

1-(3-chloro-phenyl)-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undecan-3-one

2-(3-chlorophenyl)malonic acid diethyl ester

3-chloro-N-phenylbenzamide