C₃₅H₄₈O₂Si

Base Information

• Chemical Name: C₃₅H₄₈O₂Si
• CAS No.: 1429123-41-0
• Molecular Formula: C₃₅H₄₈O₂Si
• Molecular Weight: 528.85
• Mol file: 1429123-41-0.mol

Synonyms:C₃₅H₄₈O₂Si

Chemical Property of C₃₅H₄₈O₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₄₈O₂Si

There total 11 articles about C₃₅H₄₈O₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

C19H30O2 (1429123-40-9) + tert-butylchlorodiphenylsilane (58479-61-1) → C35H48O2Si (1429123-41-0)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol400508s

Reference yield:

(2E,4Z)-5-iodo-2,4-dimethylpenta-2,4-dienal (861909-36-6) → C35H48O2Si (1429123-41-0)

Guidance literature:

Multi-step reaction with 9 steps

1.1: di-n-butylboryl trifluoromethanesulfonate; triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

1.2: 3 h / -78 °C / Inert atmosphere

2.1: trimethylaluminum / toluene; tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

2.2: 1 h / -20 - 0 °C / Inert atmosphere

3.1: 2,6-dimethylpyridine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

4.1: diisobutylaluminium hydride / toluene; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

5.1: lithium tert-butoxide / hexane; dichloromethane / 20 °C / Inert atmosphere

6.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(I) thiophene-2-carboxylate / benzene / 18 h / 65 - 125 °C / Darkness; Inert atmosphere; Schlenk technique

7.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 55 °C / Molecular sieve; Inert atmosphere

8.1: diisobutylaluminium hydride / dichloromethane; toluene / 1.5 h / -78 °C / Inert atmosphere

9.1: 1H-imidazole / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With 1H-imidazole; 2,6-dimethylpyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(I) thiophene-2-carboxylate; di-n-butylboryl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; trimethylaluminum; diisobutylaluminium hydride; triethylamine; lithium tert-butoxide; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide; toluene; benzene; 6.1: |Diels-Alder Cycloaddition;

DOI:10.1021/ol400508s

Reference yield:

C20H24INO4 (1429123-31-8) → C35H48O2Si (1429123-41-0)

Guidance literature:

Multi-step reaction with 8 steps

1.1: trimethylaluminum / toluene; tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: 1 h / -20 - 0 °C / Inert atmosphere

2.1: 2,6-dimethylpyridine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

3.1: diisobutylaluminium hydride / toluene; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

4.1: lithium tert-butoxide / hexane; dichloromethane / 20 °C / Inert atmosphere

5.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(I) thiophene-2-carboxylate / benzene / 18 h / 65 - 125 °C / Darkness; Inert atmosphere; Schlenk technique

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 55 °C / Molecular sieve; Inert atmosphere

7.1: diisobutylaluminium hydride / dichloromethane; toluene / 1.5 h / -78 °C / Inert atmosphere

8.1: 1H-imidazole / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With 1H-imidazole; 2,6-dimethylpyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(I) thiophene-2-carboxylate; tetrabutyl ammonium fluoride; trimethylaluminum; diisobutylaluminium hydride; lithium tert-butoxide; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide; toluene; benzene; 5.1: |Diels-Alder Cycloaddition;

DOI:10.1021/ol400508s

upstream raw materials:

(2E,4Z)-5-iodo-2,4-dimethylpenta-2,4-dienal

C₂₀H₂₄INO₄

C₁₆H₂₉IO₂Si

C₁₂H₂₀INO₃

Downstream raw materials:

C₃₅H₄₆O₂Si