tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate

Base Information

Chemical Name:tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate
CAS No.:1080018-66-1
Molecular Formula:C₄₀H₅₂Cl₂N₁₆O₈
Molecular Weight:955.861
Hs Code.:

tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate

Synonyms:tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate

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Chemical Property of tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate

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Technology Process of tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate

There total 8 articles about tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 742102-31-4
tert-butyl (3,5-diamino-6-chloropyrazine-2-carboxamido)(methylthio)methylene carbamate

: [4-(4-amino-piperidine-1-carbonyl)-phenyl]-(4-amino-piperidin-1-yl)-methanone dihydrochloride

: 1080018-66-1
tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate

Guidance literature:: With triethylamine; at 20 - 60 ℃; for 48h;

Reference yield:

: 1080018-69-4
3,5-diamino-6-chloropyrazine-2-carboxylic acid lithium salt

: 1080018-66-1
tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: HATU / N,N-dimethyl-formamide / 2 h / 20 °C

1.2: 20 - 50 °C

2.1: triethylamine / 48 h / 20 - 60 °C

With triethylamine; HATU; In N,N-dimethyl-formamide;

Reference yield:

: 173998-77-1
tert-butyl [amino(methylthio)methylene]carbamate

: 1080018-66-1
tert-butyl (1,1'-(1,4-phenylene)bis(oxomethylene)bis(piperidine-4,1-diyl))bis(azanediyl)bis((3,5-diamino-6-chloropyrazine-2-carboxamido)methan-1-yl-1-ylidene)dicarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: HATU / N,N-dimethyl-formamide / 2 h / 20 °C

1.2: 20 - 50 °C

2.1: triethylamine / 48 h / 20 - 60 °C

With triethylamine; HATU; In N,N-dimethyl-formamide;