Tert-butyl N-(1,3-diaminopropan-2-yl)carbamate

Base Information

Chemical Name:Tert-butyl N-(1,3-diaminopropan-2-yl)carbamate
CAS No.:213475-74-2
Molecular Formula:C8H19 N3 O2
Molecular Weight:189.258
Hs Code.:
European Community (EC) Number:881-839-7
Nikkaji Number:J963.306E
Mol file:213475-74-2.mol

Synonyms:Tert-butyl N-(1,3-diaminopropan-2-yl)carbamate;213475-74-2;tert-butyl (1,3-diaminopropan-2-yl)carbamate;SCHEMBL2846888;AKOS026727603;CS-0265069;FT-0766778;tert-butyl(1,3-diaminopropan-2-yl)carbamate;EN300-96285;F70861;Z1262632946;[2-Amino-1-(aminomethyl)ethyl]carbamic acid tert-butyl ester;Carbamic acid, [2-amino-1-(aminomethyl)ethyl]-, 1,1-dimethylethyl ester (9CI)

Suppliers and Price of Tert-butyl N-(1,3-diaminopropan-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-butylN-(1,3-diaminopropan-2-yl)carbamate
5mg
$ 65.00

AK Scientific
Tert-butylN-(1,3-diaminopropan-2-yl)carbamate
500mg
$ 985.00

Total 4 raw suppliers

Chemical Property of Tert-butyl N-(1,3-diaminopropan-2-yl)carbamate

Chemical Property:

Boiling Point:331.6±32.0 °C(Predicted)
PKA:11.76±0.46(Predicted)
PSA：90.37000
Density:1.047±0.06 g/cm3(Predicted)
LogP:1.58860
XLogP3:-0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:189.147726857
Heavy Atom Count:13
Complexity:161

Purity/Quality:

98% ^*data from raw suppliers

tert-butylN-(1,3-diaminopropan-2-yl)carbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CN)CN

Technology Process of Tert-butyl N-(1,3-diaminopropan-2-yl)carbamate

There total 6 articles about Tert-butyl N-(1,3-diaminopropan-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 213475-67-3
[2-benzyloxycarbonylamino-1-(benzyloxycarbonylaminomethyl)ethyl]carbamic acid tert-butyl ester

: 213475-74-2
tert-butyl (1,3-diaminopropan-2-yl)carbamate

Guidance literature:: With 10% Pd/C; hydrogen; In methanol; at 20 ℃; for 2h; under 760.051 Torr;
DOI:10.1016/j.ejmech.2008.02.021

Reference yield: 99.0%

: 213475-73-1
tert-butyl (1,3-diazidopropan-2-yl)carbamate

: 213475-74-2
tert-butyl (1,3-diaminopropan-2-yl)carbamate

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 750.06 Torr;
DOI:10.1055/s-1998-2128

Reference yield:

: 125414-41-7
N-Boc-serinol

: 213475-74-2
tert-butyl (1,3-diaminopropan-2-yl)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / Et₃N / CH₂Cl₂ / 1.) 0 deg C, 1 h, 2.) r.t., 30 min

2: 81 percent / NaN₃, 15-crown-5 / dimethylformamide / 12 h / 60 - 70 °C

3: 99 percent / H₂ / 5percent Pd/C / methanol / 750.06 Torr

With sodium azide; 15-crown-5; hydrogen; triethylamine; palladium on activated charcoal; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/s-1998-2128