(8S,9S)-6'-methoxy-9-phenyl-9-cinchonanol

Base Information

• Chemical Name: (8S,9S)-6'-methoxy-9-phenyl-9-cinchonanol
• CAS No.: 1393601-70-1
• Molecular Formula: C₂₆H₂₈N₂O₂
• Molecular Weight: 400.521
• Mol file: 1393601-70-1.mol

Synonyms:(8S,9S)-6'-methoxy-9-phenyl-9-cinchonanol

Chemical Property of (8S,9S)-6'-methoxy-9-phenyl-9-cinchonanol

Chemical Property:

Purity/Quality:

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Technology Process of (8S,9S)-6'-methoxy-9-phenyl-9-cinchonanol

There total 1 articles about (8S,9S)-6'-methoxy-9-phenyl-9-cinchonanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

(8S,9S)-6'-methoxy-9-phenyl-cinchonan (1007362-77-7) → (8S,9S)-6'-methoxy-9-phenyl-9-cinchonanol (1393601-70-1) + (8S,9R)-6'-methoxy-9-phenyl-9-cinchonanol (1393601-69-8)

Guidance literature:

(8S,9S)-6'-methoxy-9-phenyl-cinchonan; With dimsylsodium; In dimethyl sulfoxide; at 20 ℃; for 0.333333h; Inert atmosphere;

With oxygen; In dimethyl sulfoxide; for 48h;

With sodium hydrogensulfite; In water; dimethyl sulfoxide; for 0.5h; optical yield given as %de; diastereoselective reaction;

DOI:10.1016/j.tetasy.2012.05.024

upstream raw materials:

(8S,9S)-6'-methoxy-9-phenyl-cinchonan