2-Methyl-5-benzofuranamine

Base Information

Chemical Name:2-Methyl-5-benzofuranamine
CAS No.:26210-75-3
Molecular Formula:C9H9NO
Molecular Weight:147.177
Hs Code.:2932999099
DSSTox Substance ID:DTXSID40390139
Wikidata:Q82186577
Mol file:26210-75-3.mol

Synonyms:26210-75-3;2-METHYL-5-BENZOFURANAMINE;2-Methylbenzofuran-5-amine;5-Amino-2-methylbenzofuran;2-methyl-1-benzofuran-5-amine;2-Methyl-benzofuran-5-ylamine;2-methylbenzo[b]furan-5-ylamine;(2-methyl-1-benzofuran-5-yl)amine;2-methyl-5-aminobenzofuran;5-Amino-2-methyl benzofuran;5-Benzofuranamine, 2-methyl-;5-Amino-2-methylbenzo[b]furan;SCHEMBL2790760;DTXSID40390139;AC5757;MFCD06617946;STK503465;AKOS000303142;CCG-321496;SY045624;BB 0252867;CS-0439142;FT-0694758;EN300-254549;(2-Methyl-1-benzofuran-5-yl)amine, AldrichCPR;A919254

Suppliers and Price of 2-Methyl-5-benzofuranamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methyl-5-benzofuranamine
2.5g
$ 500.00

TRC
2-Methyl-5-benzofuranamine
5g
$ 895.00

American Custom Chemicals Corporation
5-AMINO-2-METHYLBENZOFURAN 95.00%
1G
$ 750.75

American Custom Chemicals Corporation
5-AMINO-2-METHYLBENZOFURAN 95.00%
0.5G
$ 682.00

AK Scientific
2-Methyl-5-benzofuranamine
1g
$ 1275.00

Total 8 raw suppliers

Chemical Property of 2-Methyl-5-benzofuranamine

Chemical Property:

Vapor Pressure:0.00327mmHg at 25°C
Refractive Index:1.648
Boiling Point:282.9 °C at 760 mmHg
PKA:3.95±0.10(Predicted)
Flash Point:124.9 °C
PSA：39.16000
Density:1.178 g/cm³
LogP:2.90460
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:147.068413911
Heavy Atom Count:11
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

2-Methyl-5-benzofuranamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(O1)C=CC(=C2)N
Uses 2-Methyl-5-benzofuranamine is a benzofuranamide analogs which potentially exhibit low nanomolar inhibition of Cryptosporidium parvum IMP dehydrogenase (CpIMPDH).

Technology Process of 2-Methyl-5-benzofuranamine

There total 5 articles about 2-Methyl-5-benzofuranamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 14146-09-9
2-methyl-5-nitrobenzofuran

: 26210-75-3
5-amino-2-methylbenzofuran

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In methanol; for 4h; under 760.051 Torr;

Reference yield: 71.0%

: 23968-38-9
N-(2-methylbenzofuran-5-yl)acetamide

: 26210-75-3
5-amino-2-methylbenzofuran

Guidance literature:: With hydrogenchloride; water; In methanol; at 80 ℃; for 20h; Inert atmosphere;
DOI:10.1002/anie.202103910

Reference yield:

: 103-90-2,8055-08-1
4-acetaminophenol

: 26210-75-3
5-amino-2-methylbenzofuran

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 24 h / 60 °C / Inert atmosphere

2: N,N-diethylaniline; cesium fluoride / 24 h / 210 °C / Inert atmosphere

3: water; hydrogenchloride / methanol / 20 h / 80 °C / Inert atmosphere

With hydrogenchloride; water; potassium carbonate; cesium fluoride; N,N-diethylaniline; In methanol; acetone;
DOI:10.1002/anie.202103910