1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(pyridin-4-yl)cyclopentanecarboxamide

Base Information

Chemical Name:1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(pyridin-4-yl)cyclopentanecarboxamide
CAS No.:1382485-97-3
Molecular Formula:C₂₁H₂₁N₅O
Molecular Weight:359.431
Hs Code.:

Synonyms:1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(pyridin-4-yl)cyclopentanecarboxamide

Suppliers and Price of 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(pyridin-4-yl)cyclopentanecarboxamide

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Chemical Property of 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(pyridin-4-yl)cyclopentanecarboxamide

Chemical Property:

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Technology Process of 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(pyridin-4-yl)cyclopentanecarboxamide

There total 2 articles about 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(pyridin-4-yl)cyclopentanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 402960-38-7
5-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)pyrimidin-2-ylamine

: 1382486-36-3
C₁₇H₁₇BrN₂O

: 1382485-97-3
1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(pyridin-4-yl)cyclopentanecarboxamide

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 100 ℃; for 1h;

Reference yield:

: 504-24-5
4-aminopyridine

: 1382486-66-9
C₁₇H₁₅BrN₄O₂

: 1382485-97-3
1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(pyridin-4-yl)cyclopentanecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.25 h / 20 °C

1.2: 1 h / 120 °C / Microwave irradiation

2.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 1 h / 100 °C

With sodium hydride; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;