(S)-2-[(2-Nitro-benzyl)-(thiophene-2-sulfonyl)-amino]-propionic acid

Base Information

• Chemical Name: (S)-2-[(2-Nitro-benzyl)-(thiophene-2-sulfonyl)-amino]-propionic acid
• CAS No.: 351527-11-2
• Molecular Formula: C₁₄H₁₄N₂O₆S₂
• Molecular Weight: 370.407
• Mol file: 351527-11-2.mol

Synonyms:(S)-2-[(2-Nitro-benzyl)-(thiophene-2-sulfonyl)-amino]-propionic acid

Chemical Property of (S)-2-[(2-Nitro-benzyl)-(thiophene-2-sulfonyl)-amino]-propionic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of (S)-2-[(2-Nitro-benzyl)-(thiophene-2-sulfonyl)-amino]-propionic acid

There total 1 articles about (S)-2-[(2-Nitro-benzyl)-(thiophene-2-sulfonyl)-amino]-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitrobenzyl chloride (612-23-7) → (S)-2-[(2-Nitro-benzyl)-(thiophene-2-sulfonyl)-amino]-propionic acid (351527-11-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / acetonitrile / 10 h / 20 °C

2: aq. NaHCO₃ / acetone / 20 °C

With sodium hydrogencarbonate; triethylamine; In acetone; acetonitrile;

DOI:10.1021/jm010087e

Reference yield:

(S)-2-[(2-Nitro-benzyl)-(thiophene-2-sulfonyl)-amino]-propionic acid (351527-11-2) → N-hydroxy-2-[(2-nitro-benzyl)-(thiophene-2-sulfonyl)-amino]-propionamide

Guidance literature:

With hydroxylamine hydrochloride; triethylamine; diisopropyl-carbodiimide; In acetonitrile; at 4 ℃; for 12h;

DOI:10.1021/jm010087e

upstream raw materials:

2-nitrobenzyl chloride