3-TRIFLUOROMETHYLBENZOIC ANHYDRIDE

Base Information

• Chemical Name: 3-TRIFLUOROMETHYLBENZOIC ANHYDRIDE
• CAS No.: 25753-15-5
• Molecular Formula: C16H8 F6 O3
• Molecular Weight: 362.228
• Hs Code.: 2916399090
• Mol file: 25753-15-5.mol

Synonyms:Benzoicacid, 3-(trifluoromethyl)-, anhydride (9CI); m-Toluic acid, a,a,a-trifluoro-, anhydride (8CI); 3-(Trifluoromethyl)benzoic acid anhydride;3-(Trifluoromethyl)benzoic anhydride

Chemical Property of 3-TRIFLUOROMETHYLBENZOIC ANHYDRIDE

Chemical Property:

• Vapor Pressure: 3.27E-06mmHg at 25°C
• Melting Point: 74-78℃
• Refractive Index: 1.486
• Boiling Point: 387.6°C at 760 mmHg
• Flash Point: 181.7°C
• PSA: 43.37000
• Density: 1.427g/cm³
• LogP: 4.72140
• Sensitive.: Moisture Sensitive

Purity/Quality:

98% ^*data from raw suppliers

3-(Trifluoromethyl)benzoicanhydride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-TRIFLUOROMETHYLBENZOIC ANHYDRIDE

There total 1 articles about 3-TRIFLUOROMETHYLBENZOIC ANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-trifluoromethyl-benzoic acid anhydride (25753-15-5)

Guidance literature:

Thermolyse von /BRN= 47307/ (als 2. Produkt entsteht Isophthalsaeure);

Reference yield: 77.0%

3-Phenyl-1-propanol (122-97-4) + 3-trifluoromethyl-benzoic acid anhydride (25753-15-5) + 3-Phenylpropionic acid (501-52-0) → 3-phenylpropionic acid 3-phenylpropyl ester (60045-27-4) + 3-phenylpropyl ester 3-trifluoromethylbenzoic acid

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/jo030367x

Reference yield: 54.0%

bicyclo[2.2.1]hepta-2,5-diene (121-46-0) + 3-trifluoromethyl-benzoic acid anhydride (25753-15-5) → 2-(m-trifluoromethylphenoyl)-3-(m-trifluoromethylphenoyloxy)bicyclo[2.2.1]hept-5-ene

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 1,3-bis-(diphenylphosphino)propane; In tetrahydrofuran; for 6h; Inert atmosphere; Reflux;

DOI:10.1039/c4cc07759h

Downstream raw materials:

3-(2,2-dichloro-1,1-difluoro-ethyl)-5-(3-trifluoromethyl-phenyl)-[1,2,4]oxadiazole

3-phenylpropionic acid 3-phenylpropyl ester

ethenyl 3-(trifluoromethyl)benzoate