5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid

Base Information

• Chemical Name: 5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid
• CAS No.: 1000878-09-0
• Molecular Formula: C₂₆H₂₆O₉
• Molecular Weight: 482.487
• Mol file: 1000878-09-0.mol

Synonyms:5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid

Chemical Property of 5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid

There total 1 articles about 5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

glutaric anhydride, (108-55-4) + curcumin (458-37-7) → 5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid (1000878-09-0)

Guidance literature:

With dmap; triethylamine; In tetrahydrofuran; Heating / reflux;

Reference yield: 80.0%

5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid (1000878-09-0) + 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose (4064-06-6) → C38H44O14 (1330528-81-8)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;

Reference yield: 61.0%

5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid (1000878-09-0) + C42H54N6O5 → C68H78N6O13

Guidance literature:

5-(4-((1E, 6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1, 6-dien-1-yl)-2-methoxyphenoxy)-5-oxopentanoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; for 0.5h;

C₄₂H₅₄N₆O₅; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1016/j.ejmech.2018.01.099

upstream raw materials:

glutaric anhydride,

curcumin

Downstream raw materials:

C₃₈H₄₄O₁₄