4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

Base Information

Chemical Name:4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine
CAS No.:1361961-11-6
Molecular Formula:C₁₈H₁₈ClFN₄O₃S
Molecular Weight:424.883
Hs Code.:

Synonyms:4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

Suppliers and Price of 4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

There total 4 articles about 4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 3240-94-6
N-(2-chlorethyl)morpholine

: 1361961-10-5
4-chloror-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine

: 1361961-11-6
4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

Guidance literature:: 4-chloror-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine; With potassium tert-butylate; In N,N-dimethyl-formamide; at 0 ℃; for 0.25h;

N-(2-chlorethyl)morpholine; With sodium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 15h;

Reference yield:

: 1361960-94-2
4-chloro-2-(4-fluorophenylthio)-7H-pyrrolo[2,3-d]pyrimidine

: 1361961-11-6
4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

Guidance literature:: Multi-step reaction with 2 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane; N,N-dimethyl-formamide / 0 - 20 °C

2.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.25 h / 0 °C

2.2: 15 h / 20 °C

With potassium tert-butylate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1361960-93-1
2-(4-fluorophenylthio)-7H-pyrrolo[2,3-d]pyrimidin-4-ol

: 1361961-11-6
4-(2-(4-chloro-2-(4-fluorophenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

Guidance literature:: Multi-step reaction with 3 steps

1.1: trichlorophosphate / 1 h / 110 °C

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane; N,N-dimethyl-formamide / 0 - 20 °C

3.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.25 h / 0 °C

3.2: 15 h / 20 °C

With potassium tert-butylate; 3-chloro-benzenecarboperoxoic acid; trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide;