Technology Process of C42H42BN
There total 3 articles about C42H42BN which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-bromo-N,N-dimethylaniline;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 1h;
Inert atmosphere;
With
zinc(II) chloride;
In
tetrahydrofuran; hexane;
at -78 - 0 ℃;
for 2h;
Inert atmosphere;
1-iodo-8-p-dimesitylboronylphenylnaphthalene;
With
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; hexane;
at 0 - 20 ℃;
for 41h;
Inert atmosphere;
DOI:10.1021/ol102749y
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / Inert atmosphere
1.2: Inert atmosphere
1.3: Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
2.2: 2 h / -78 - 0 °C / Inert atmosphere
2.3: 41 h / 0 - 20 °C / Inert atmosphere
With
n-butyllithium;
In
tetrahydrofuran; hexane;
1.3: Negishi coupling / 2.3: Negishi coupling;
DOI:10.1021/ol102749y
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / Inert atmosphere
1.2: Inert atmosphere
1.3: Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
2.2: 2 h / -78 - 0 °C / Inert atmosphere
2.3: 41 h / 0 - 20 °C / Inert atmosphere
With
n-butyllithium;
In
tetrahydrofuran; hexane;
1.3: Negishi coupling / 2.3: Negishi coupling;
DOI:10.1021/ol102749y
