(Z)-β,o-dibromo-β-trimethylsilylstyrene

Base Information

• Chemical Name: (Z)-β,o-dibromo-β-trimethylsilylstyrene
• CAS No.: 160566-50-7
• Molecular Formula: C₁₁H₁₄Br₂Si
• Molecular Weight: 334.126
• Mol file: 160566-50-7.mol

Synonyms:(Z)-β,o-dibromo-β-trimethylsilylstyrene

Chemical Property of (Z)-β,o-dibromo-β-trimethylsilylstyrene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-β,o-dibromo-β-trimethylsilylstyrene

There total 3 articles about (Z)-β,o-dibromo-β-trimethylsilylstyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-bromo-1-(trimethylsilylethynyl)benzene (38274-16-7) → (Z)-β,o-dibromo-β-trimethylsilylstyrene (160566-50-7)

Guidance literature:

2-bromo-1-(trimethylsilylethynyl)benzene; With diisobutylaluminium hydride; In hexane; at 20 ℃; Inert atmosphere;

With N-Bromosuccinimide; In hexane; for 0.5h; Cooling with ice;

DOI:10.1039/d0dt02224a

Reference yield:

1-Bromo-2-iodobenzene (583-55-1) → (Z)-β,o-dibromo-β-trimethylsilylstyrene (160566-50-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / Pd(PPh₃)2Cl₂, CuI, Et₂NH / 3.5 h / Ambient temperature

2: 1.) DIBAL-H, 2.) NBS / 1.) hexane, RT, 3 d, 2.) hexane, a) -20 deg C, 30 min, b) RT, 1 h

With bis-triphenylphosphine-palladium(II) chloride; N-Bromosuccinimide; copper(l) iodide; diisobutylaluminium hydride; diethylamine;

DOI:10.1248/cpb.42.1437

Reference yield:

trimethylsilylacetylene (1066-54-2) → (Z)-β,o-dibromo-β-trimethylsilylstyrene (160566-50-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / Pd(PPh₃)2Cl₂, CuI, Et₂NH / 3.5 h / Ambient temperature

2: 1.) DIBAL-H, 2.) NBS / 1.) hexane, RT, 3 d, 2.) hexane, a) -20 deg C, 30 min, b) RT, 1 h

With bis-triphenylphosphine-palladium(II) chloride; N-Bromosuccinimide; copper(l) iodide; diisobutylaluminium hydride; diethylamine;

DOI:10.1248/cpb.42.1437

upstream raw materials:

2-bromo-1-(trimethylsilylethynyl)benzene

1-Bromo-2-iodobenzene

trimethylsilylacetylene

Downstream raw materials:

1-phenyl-2-trimethylsilylbenzo[b]arsole

2-bromobenzo[b]phosphole P-oxide

1-phenyl-1-benzarsole

3-hydroxybenzo[b]tellurophene