3-[2-(Trifluoromethyl)phenyl]prop-2-enoyl chloride

Base Information

Chemical Name:3-[2-(Trifluoromethyl)phenyl]prop-2-enoyl chloride
CAS No.:209619-25-0
Molecular Formula:C10H6 Cl F3 O
Molecular Weight:234.605
Hs Code.:2916399090
DSSTox Substance ID:DTXSID10694237
Mol file:209619-25-0.mol

Synonyms:3-[2-(trifluoromethyl)phenyl]prop-2-enoyl chloride;DTXSID10694237;2-(trifluoro-methyl)cinnamoyl chloride

Suppliers and Price of 3-[2-(Trifluoromethyl)phenyl]prop-2-enoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

CHESS?
SG000416:3-(2-Trifluoromethyl-phenyl)-acryloylchloride 98
1 g
$ 420.00

American Custom Chemicals Corporation
3-(2-TRIFLUOROMETHYL-PHENYL)-ACRYLOYL CHLORIDE 95.00%
5MG
$ 498.66

Total 5 raw suppliers

Chemical Property of 3-[2-(Trifluoromethyl)phenyl]prop-2-enoyl chloride

Chemical Property:

PSA：17.07000
LogP:3.48400
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:234.0059270
Heavy Atom Count:15
Complexity:260

Purity/Quality:

98%min ^*data from raw suppliers

SG000416:3-(2-Trifluoromethyl-phenyl)-acryloylchloride 98 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 34
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C=CC(=O)Cl)C(F)(F)F

Technology Process of 3-[2-(Trifluoromethyl)phenyl]prop-2-enoyl chloride

There total 2 articles about 3-[2-(Trifluoromethyl)phenyl]prop-2-enoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-trifluoromethylcinnamic acid

: 209619-25-0
C₁₀H₆ClF₃O

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; toluene; at 20 - 90 ℃;

Reference yield:

: 447-61-0
2-Trifluoromethylbenzaldehyde

: 209619-25-0
C₁₀H₆ClF₃O

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; piperidine / 3 h / Reflux

2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 24 h / 20 °C

With piperidine; pyridine; oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1016/j.bioorg.2021.105465