4-{[1-hydroxy-3-oxo-1-(phenoxymethyl)isoindol-2-yl]methyl}phenyl acetate

Base Information

Chemical Name:4-{[1-hydroxy-3-oxo-1-(phenoxymethyl)isoindol-2-yl]methyl}phenyl acetate
CAS No.:1401522-37-9
Molecular Formula:C₂₄H₂₁NO₅
Molecular Weight:403.434
Hs Code.:

Synonyms:4-{[1-hydroxy-3-oxo-1-(phenoxymethyl)isoindol-2-yl]methyl}phenyl acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-{[1-hydroxy-3-oxo-1-(phenoxymethyl)isoindol-2-yl]methyl}phenyl acetate

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Technology Process of 4-{[1-hydroxy-3-oxo-1-(phenoxymethyl)isoindol-2-yl]methyl}phenyl acetate

There total 1 articles about 4-{[1-hydroxy-3-oxo-1-(phenoxymethyl)isoindol-2-yl]methyl}phenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 58613-67-5
potassium phenoxyacetate

: 630393-48-5
2-(4-acetoxybenzyl) isoindoline-1,3-dione

: 1401522-37-9
4-{[1-hydroxy-3-oxo-1-(phenoxymethyl)isoindol-2-yl]methyl}phenyl acetate

Guidance literature:: With water; In acetone; for 4h; Irradiation; Inert atmosphere;
DOI:10.1016/j.tetlet.2012.07.142

Reference yield:

: 1401522-37-9
4-{[1-hydroxy-3-oxo-1-(phenoxymethyl)isoindol-2-yl]methyl}phenyl acetate

: 1401522-54-0
(E)-2-(4-hydroxybenzyl)-3-(phenoxymethylene)isoindolin-1-one

: 1401522-56-2
(Z)-2-(4-hydroxybenzyl)-3-(phenoxymethylene)isoindolin-1-one

Guidance literature:: With hydrogenchloride; In water; for 5h; Overall yield = 89 %; diastereoselective reaction; Reflux;
DOI:10.1016/j.tetlet.2012.07.142