N₁-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N₂-((S)-1-methyl-2-methylthioethyl)phthalamide

Base Information

• Chemical Name: N₁-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N₂-((S)-1-methyl-2-methylthioethyl)phthalamide
• CAS No.: 916974-90-8
• Molecular Formula: C₂₈H₂₅ClF₆N₂O₂S
• Molecular Weight: 603.028

Synonyms:N₁-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N₂-((S)-1-methyl-2-methylthioethyl)phthalamide

Chemical Property of N₁-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N₂-((S)-1-methyl-2-methylthioethyl)phthalamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N₁-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N₂-((S)-1-methyl-2-methylthioethyl)phthalamide

There total 3 articles about N₁-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N₂-((S)-1-methyl-2-methylthioethyl)phthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3Z/E)-4-chloro-3-{[(1S)-1-methyl-2-(methylthio)ethyl]imino}-2-benzofuran-1(3H)-one (878533-80-3) + 4-(3,5-bis-trifluoromethyl-benzyl)-2-methylaniline (916975-21-8) → N1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N2-((S)-1-methyl-2-methylthioethyl)phthalamide (916974-90-8)

Guidance literature:

toluene-4-sulfonic acid; In acetonitrile; at 20 ℃; for 3h;

Reference yield:

4-(chloromethyl)-2-methyl-1-nitro-benzene (18515-14-5) → N1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N2-((S)-1-methyl-2-methylthioethyl)phthalamide (916974-90-8)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 2 h / 85 °C

2: titanium(III) chloride; ammonium acetate; water / acetone / 12 h / 20 °C

3: toluene-4-sulfonic acid / acetonitrile / 3 h / 20 °C

With titanium(III) chloride; ammonium acetate; water; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; toluene-4-sulfonic acid; In 1,2-dimethoxyethane; water; acetone; acetonitrile;

Reference yield:

4-(3,5-bis-trifluoromethyl-benzyl)-2-methyl-nitrobenzene (916975-20-7) → N1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N2-((S)-1-methyl-2-methylthioethyl)phthalamide (916974-90-8)

Guidance literature:

Multi-step reaction with 2 steps

1: titanium(III) chloride; ammonium acetate; water / acetone / 12 h / 20 °C

2: toluene-4-sulfonic acid / acetonitrile / 3 h / 20 °C

With titanium(III) chloride; ammonium acetate; water; toluene-4-sulfonic acid; In acetone; acetonitrile;

upstream raw materials:

(3Z/E)-4-chloro-3-{[(1S)-1-methyl-2-(methylthio)ethyl]imino}-2-benzofuran-1(3H)-one

4-(3,5-bis-trifluoromethyl-benzyl)-2-methylaniline

4-(3,5-bis-trifluoromethyl-benzyl)-2-methyl-nitrobenzene

4-(chloromethyl)-2-methyl-1-nitro-benzene

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 916974-90-8 N₁-[4-(3,5-bis-trifluoromethyl-benzyl)-2-methylphenyl]-3-chloro-N₂-((S)-1-methyl-2-methylthioethyl)phthalamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send