Taurodeoxycholic Acid, Sodium Salt

Base Information

• Chemical Name: Taurodeoxycholic Acid, Sodium Salt
• CAS No.: 207737-97-1
• Molecular Formula: C26H45 N O6 S . x H2 O . Na
• Molecular Weight: 539.705
• Hs Code.: 29242998
• European Community (EC) Number: 214-652-0,805-952-8
• NCI Thesaurus Code: C80659
• Mol file: 207737-97-1.mol

Synonyms:Acid, Taurodeoxycholic;Deoxycholate, Taurine;Deoxycholyltaurine;Sodium Taurodeoxycholate;Taurine Deoxycholate;Taurodeoxycholate;Taurodeoxycholate, Sodium;Taurodeoxycholic Acid

Chemical Property of Taurodeoxycholic Acid, Sodium Salt

Chemical Property:

• Melting Point: 168 °C (dec.)(lit.)
• PSA: 144.37000
• LogP: 4.46210
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: H2O: soluble0.5M, clear, colorless to faintly yellow
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 521.27870358
• Heavy Atom Count: 35
• Complexity: 864

Purity/Quality:

97%, ^*data from raw suppliers

Sodium taurodeoxycholate hydrate ≥95% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
• Recent EU Clinical Trials: A Randomized, Double-blinded, Placebo-controlled, Parallel-treatment Group, Adaptive Design, Multi-center, Phase 2b/3 Trial to Evaluate Efficacy and Safety of NuSepin? Intravenous Infusion in COVID-19 Pneumonia Patients
• Description: Sodium taurodeoxycholate hydrate is a bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. It has also been used in a study to investigate polymorphic behavior in protein surfactant mixtures.Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. It has also been used in a study to investigate polymorphic behavior in protein-surfactant mixtures.
• Uses: A hydrate form of sodium taurodeoxycholate (T009005), a steroid which rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.