6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine

Base Information

Chemical Name:6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine
CAS No.:509953-12-2
Molecular Formula:C₁₉H₁₈BrN₃O₄
Molecular Weight:432.274
Hs Code.:

Synonyms:6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine

Suppliers and Price of 6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine

There total 1 articles about 6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 5392-10-9
2-bromo-4,5-dimethoxybenzaldehyde

: 54637-91-1
5-methoxy-3-phenyl-1,2,4-triazine

: 509953-12-2
6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine

Guidance literature:: 5-methoxy-3-phenyl-1,2,4-triazine; With 2,2,6,6-tetramethylpiperidinyl-lithium; In tetrahydrofuran; hexane; at -95 ℃; for 1h;

2-bromo-4,5-dimethoxybenzaldehyde; In tetrahydrofuran; hexane; at -95 ℃; for 1h;
DOI:10.1055/s-2002-35630

Reference yield: 91.0%

: 509953-12-2
6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine

: 509953-16-6
6-(2-bromo-3,4-dimethoxybenzoyl)-5-methoxy-3-phenyl-1,2,4-triazine

Guidance literature:: With manganese(IV) oxide; In tetrahydrofuran; at 20 ℃; for 5h;
DOI:10.1055/s-2002-35630

Reference yield:

: 509953-12-2
6-(2-bromo-3,4-dimethoxy-α-hydroxybenzyl)-5-methoxy-3-phenyl-1,2,4-triazine

: 4-butyl-1,6,7-trimethoxy-3-phenyl-2-azafluorenone

Guidance literature:: Multi-step reaction with 3 steps

1.1: 91 percent / MnO₂ / tetrahydrofuran / 5 h / 20 °C

2.1: Pr₃N; CuI / PdCl₂(Ph₃P)2 / dimethylformamide / 0.33 h / 20 °C

2.2: dimethylformamide

3.1: 78 mg / 1.5 h / 100 - 120 °C

With tri-n-propylamine; manganese(IV) oxide; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; N,N-dimethyl-formamide; 2.2: Sonogashira reaction / 3.1: intramolecular Diels-Alder reaction;
DOI:10.1055/s-2002-35630