(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-1-propyl-cyclooctanecarbonitrile

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Chemical Name:(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-1-propyl-cyclooctanecarbonitrile
CAS No.:152297-30-8
Molecular Formula:C₁₈H₃₁N₃O
Molecular Weight:305.464
Hs Code.:

Synonyms:(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-1-propyl-cyclooctanecarbonitrile

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Chemical Property of (S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-1-propyl-cyclooctanecarbonitrile

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Technology Process of (S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-1-propyl-cyclooctanecarbonitrile

There total 1 articles about (S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-1-propyl-cyclooctanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59983-39-0,187035-29-6
(S)-1-amino-2-(methoxymethyl)pyrrolidine

: 152297-30-8
(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-1-propyl-cyclooctanecarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / p-TsOH / cyclohexane / 12 h / Heating

2: 1) LDA / 1) Et₂O, -78 deg C to r.t., overnight, 2) -110 deg C to r.t.

With toluene-4-sulfonic acid; lithium diisopropyl amide; In cyclohexane;
DOI:10.1055/s-1993-25929