(S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene

Base Information

Chemical Name:(S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene
CAS No.:141806-55-5
Molecular Formula:C₃₀H₃₄N₄O₅S
Molecular Weight:562.69
Hs Code.:

(S)-(Z)-7-<N-benzyl-N-(benzyloxycarbonyl)amino>-8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene

Synonyms:(S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene

Suppliers and Price of (S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene

There total 9 articles about (S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 132317-00-1
(S)-(Z)-7--8-azido-3-octen-1-ol

: 98-59-9
p-toluenesulfonyl chloride

: 141806-55-5
(S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene

Guidance literature:: With pyridine; dmap; In dichloromethane; for 6h; Ambient temperature;
DOI:10.1021/jo00040a045

Reference yield:

: 77539-18-5,73914-82-6
(S)-(+)-2-benzylamino glutaric acid

: 141806-55-5
(S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene

Guidance literature:: Multi-step reaction with 8 steps

1: 71 percent / NaHCO₃ / H₂O / 3 h / Ambient temperature

2: 70 percent / BH₃*THF / tetrahydrofuran / 18 h / Ambient temperature

3: 88 percent / pyridine, DMAP / CH₂Cl₂ / 18 h / Ambient temperature

4: 83 percent / triphenylphosphine, diethyl azodicarboxylate, diphenylphosphoryl azide / tetrahydrofuran / 48 h / Ambient temperature

5: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 4 h / Ambient temperature

6: 1) DMSO, oxalyl chloride, 3) Et₃N / 1) CH₂Cl₂, -78 deg C, 30 min, 2) CH₂Cl₂, -78 deg C, 1 h, 3) CH₂Cl₂, -> r.t., 2 h

7: 3) 1 M HCl / 1) -78 deg C, 1 h, 2) r.t., 1 h, 3) 1 h

8: 67 percent / pyridine, DMAP / CH₂Cl₂ / 6 h / Ambient temperature

With pyridine; hydrogenchloride; dmap; borane-THF; oxalyl dichloride; diphenylphosphoranyl azide; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; dimethyl sulfoxide; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/jo00040a045

Reference yield:

: 132316-97-3
(S)-2--1,5-pentanediol

: 141806-55-5
(S)-(Z)-7--8-azido-1-<(p-tolylsulfonyl)oxy>oct-3-ene

Guidance literature:: Multi-step reaction with 6 steps

1: 88 percent / pyridine, DMAP / CH₂Cl₂ / 18 h / Ambient temperature

2: 83 percent / triphenylphosphine, diethyl azodicarboxylate, diphenylphosphoryl azide / tetrahydrofuran / 48 h / Ambient temperature

3: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 4 h / Ambient temperature

4: 1) DMSO, oxalyl chloride, 3) Et₃N / 1) CH₂Cl₂, -78 deg C, 30 min, 2) CH₂Cl₂, -78 deg C, 1 h, 3) CH₂Cl₂, -> r.t., 2 h

5: 3) 1 M HCl / 1) -78 deg C, 1 h, 2) r.t., 1 h, 3) 1 h

6: 67 percent / pyridine, DMAP / CH₂Cl₂ / 6 h / Ambient temperature

With pyridine; hydrogenchloride; dmap; oxalyl dichloride; diphenylphosphoranyl azide; tetrabutyl ammonium fluoride; dimethyl sulfoxide; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00040a045