2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester

Base Information

• Chemical Name: 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester
• CAS No.: 98387-59-8
• Molecular Formula: C₁₅H₂₆O₆
• Molecular Weight: 302.368
• Mol file: 98387-59-8.mol

Synonyms:2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester

Chemical Property of 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester

There total 2 articles about 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

diethyl 2-(ethoxycarbonylmethylene)malonate (13049-86-0) → triethyl 1,1,2-ethanetricarboxylate (7459-46-3) + 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester (98387-59-8)

Guidance literature:

In diethyl ether; at -70 - -40 ℃; for 1h;

Reference yield: 80.0%

diethyl 2-(ethoxycarbonylmethylene)malonate (13049-86-0) → triethyl 1,1,2-ethanetricarboxylate (7459-46-3) + 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester (98387-59-8)

Guidance literature:

With aluminium trichloride; lithium di-n-butylcuprate; In diethyl ether; at -70 - -40 ℃; for 1h; Product distribution; other organocopper reagent;

DOI:10.1016/0022-328X(85)80081-4

upstream raw materials:

diethyl 2-(ethoxycarbonylmethylene)malonate

Refernces

• 1、 Ibuka, Toshiro,Aoyagi, Takeshi,Kitada, Kazuko,Yoneda, Fumio,Yamamoto, Yoshinori. "DIFFERENCES IN THE REACTION OF ELECTRON DEFICIENT OLEFINS WITH ORGANOCOPPER(I)-LEWIS ACID REAGENTS AND EVIDENCE FOR A DIANIONIC EQUIVALENT". . p. C18 - C22. Retrieved 2007/10/02.