2-(4-bromo-phenoxymethyl)-2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

Base Information

Chemical Name:2-(4-bromo-phenoxymethyl)-2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole
CAS No.:1188387-17-8
Molecular Formula:C₁₃H₁₂BrN₃O₄
Molecular Weight:354.16
Hs Code.:

Synonyms:2-(4-bromo-phenoxymethyl)-2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-bromo-phenoxymethyl)-2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

Chemical Property:

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Technology Process of 2-(4-bromo-phenoxymethyl)-2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

There total 1 articles about 2-(4-bromo-phenoxymethyl)-2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1001314-80-2
2‐bromo‐1‐((2‐methyloxiran‐2‐yl)methyl)‐4‐nitro‐1H‐imidazole

: 106-41-2
4-bromo-phenol

: 1188387-17-8
2-(4-bromo-phenoxymethyl)-2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.3390/molecules25102431

Reference yield: 56.3%

: 1188387-17-8
2-(4-bromo-phenoxymethyl)-2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

: 504438-22-6
(R)‐3‐(3‐fluoro‐4‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)phenyl)‐5‐(hydroxymethyl)‐oxazolidin‐2‐one

: (5R)‐3‐(2‐fluoro‐4′‐((2‐methyl‐6‐nitro‐2,3‐dihydroimidazo[2,1‐b]oxazol‐2‐yl)methoxy)‐[1,1′‐biphenyl]‐4‐yl)‐5‐(hydroxymethyl)oxazolidin‐2‐one

Guidance literature:: With potassium carbonate; In water; N,N-dimethyl-formamide; at 80 ℃; for 3h; Inert atmosphere;
DOI:10.3390/molecules25102431

Reference yield:

: 504437-66-5
(S)‐N‐((3‐(3‐fluoro‐4‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)phenyl)‐2‐oxooxazolidin‐5‐yl)methyl)acetamide

: 1188387-17-8
2-(4-bromo-phenoxymethyl)-2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

: 1188917-96-5
N-{(S)-3-[2-fluoro-4'-(2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazol-2-ylmethoxy)-biphenyl-4-yl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; N,N-dimethyl-formamide; at 80 ℃; for 3h; Inert atmosphere;