N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline

Base Information

Chemical Name:N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline
CAS No.:1619935-26-0
Molecular Formula:C₂₁H₁₆Cl₂FN₃
Molecular Weight:400.283
Hs Code.:

Synonyms:N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline

Suppliers and Price of N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline

Chemical Property:

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Technology Process of N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline

There total 3 articles about N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.1%

: 94-99-5
2,4-Dichlorobenzyl chloride

: 73259-31-1
N-((1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline

: 1619935-26-0
N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline

Guidance literature:: With potassium carbonate; In acetonitrile; at 70 ℃;
DOI:10.1007/s11426-014-5087-x

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 1619935-26-0
N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / water / Reflux

2: sodium carbonate / ethanol / Reflux

3: potassium carbonate / acetonitrile / 70 °C

With hydrogenchloride; sodium carbonate; potassium carbonate; In ethanol; water; acetonitrile;
DOI:10.1007/s11426-014-5087-x

Reference yield:

: 4857-04-9
2-chloromethyl-1H-benzimidazole

: 1619935-26-0
N-((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)methyl)-4-fluoroaniline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / ethanol / Reflux

2: potassium carbonate / acetonitrile / 70 °C

With sodium carbonate; potassium carbonate; In ethanol; acetonitrile;
DOI:10.1007/s11426-014-5087-x