N-(4-chloro-3-amino-benzyl)-1-trifluoromethyl-cyclopropane carboxamide

Base Information

Chemical Name:N-(4-chloro-3-amino-benzyl)-1-trifluoromethyl-cyclopropane carboxamide
CAS No.:1242269-28-8
Molecular Formula:C₁₂H₁₂ClF₃N₂O
Molecular Weight:292.688
Hs Code.:

Synonyms:N-(4-chloro-3-amino-benzyl)-1-trifluoromethyl-cyclopropane carboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-chloro-3-amino-benzyl)-1-trifluoromethyl-cyclopropane carboxamide

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Technology Process of N-(4-chloro-3-amino-benzyl)-1-trifluoromethyl-cyclopropane carboxamide

There total 4 articles about N-(4-chloro-3-amino-benzyl)-1-trifluoromethyl-cyclopropane carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1242269-28-8
N-(4-chloro-3-amino-benzyl)-1-trifluoromethyl-cyclopropane carboxamide

Guidance literature:

Reference yield: 81.0%

: 1242269-27-7
N-(4-chloro-3-nitro-benzyl)-1-trifluoromethyl-cyclopropane carboxamide

: 1242269-28-8
N-(4-chloro-3-amino-benzyl)-1-trifluoromethyl-cyclopropane carboxamide

Guidance literature:: With hydrogen; Ra-Ni; In ethyl acetate; at 20 ℃; under 2250.23 Torr;

Reference yield:

: 100398-63-8
4-chloro-3-nitro-benzylamine

: 1242269-28-8
N-(4-chloro-3-amino-benzyl)-1-trifluoromethyl-cyclopropane carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / tetrahydrofuran / 20 °C

2: hydrogen / Ra-Ni / ethyl acetate / 20 °C / 2250.23 Torr

With hydrogen; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; Ra-Ni; In tetrahydrofuran; ethyl acetate;