Technology Process of C21H19NO5S
There total 4 articles about C21H19NO5S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride;
In
dichloromethane;
for 22h;
Heating;
DOI:10.1002/ejoc.200700045
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: nBuLi; tBuOK / diethyl ether; hexane; tetrahydrofuran / 0.5 h / 10 °C
1.2: 68 percent / diethyl ether; hexane; tetrahydrofuran / 2 h / -78 °C
2.1: 83 percent / POCl3 / CH2Cl2 / 1 h / Heating
3.1: 78 percent / sodium hexamethyldisilazane / tetrahydrofuran / 1.5 h / -78 °C
4.1: 43 percent / Grubbs second generation catalyst / CH2Cl2 / 22 h / Heating
With
n-butyllithium; potassium tert-butylate; sodium hexamethyldisilazane; trichlorophosphate;
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride;
In
tetrahydrofuran; diethyl ether; hexane; dichloromethane;
DOI:10.1002/ejoc.200700045
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 78 percent / sodium hexamethyldisilazane / tetrahydrofuran / 1.5 h / -78 °C
2: 43 percent / Grubbs second generation catalyst / CH2Cl2 / 22 h / Heating
With
sodium hexamethyldisilazane;
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1002/ejoc.200700045
