2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester

Base Information

Chemical Name:2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester
CAS No.:863639-47-8
Molecular Formula:C₂₂H₂₂F₂O₅
Molecular Weight:404.41
Hs Code.:

Synonyms:2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester

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Chemical Property of 2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester

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Technology Process of 2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester

There total 2 articles about 2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1-(4-benzyloxy-3,5-difluorophenyl)-2-bromopropan-1-one

: 863639-47-8
2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester

Guidance literature:: ethyl acetoacetate; With ethanol; sodium; at 0 ℃; for 0.5h;

1-(4-benzyloxy-3,5-difluorophenyl)-2-bromopropan-1-one; In ethanol; toluene;

Reference yield: 66.0%

: 1-(4-benzyloxy-3,5-difluorophenyl)-2-bromopropan-1-one

: 141-97-9
ethyl acetoacetate

: 863639-47-8
2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester

Guidance literature:: ethyl acetoacetate; With sodium ethanolate; sodium; In ethanol; at 0 ℃; for 0.5h;

1-(4-benzyloxy-3,5-difluorophenyl)-2-bromopropan-1-one; In ethanol; toluene;

Reference yield:

: 863639-47-8
2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester

: 13617-98-6
2,4-dichlorophenyldiazonium chloride

: 863639-49-0
C₂₆H₂₀Cl₂F₂N₂O₃

Guidance literature:: 2-acetyl-4-(4-benzyloxy-3,5-difluorophenyl)-3-methyl-4-oxobutyric acid ethyl ester; With sodium ethanolate; sodium; In ethanol; at 20 ℃; for 0.5h;

2,4-dichlorophenyldiazonium chloride; In ethanol; water; at 0 - 20 ℃;