Technology Process of benzyl-[2-(4-propyl-phenyl)-ethyl]-amine hydrochloride
There total 4 articles about benzyl-[2-(4-propyl-phenyl)-ethyl]-amine hydrochloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
N-benzyl-2-(4-propyl-phenyl)-acetamide;
With
diisobutylaluminium hydride;
In
toluene;
at 0 - 20 ℃;
With
hydrogenchloride;
In
diethyl ether;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran / 48 h / -78 - 20 °C
2: diisobutylaluminium hydride / toluene / 0 - 20 °C
With
diisobutylaluminium hydride;
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride;
In
tetrahydrofuran; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.17 h / 20 °C
1.2: 1 h / 20 °C
2.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran / 48 h / -78 - 20 °C
3.1: diisobutylaluminium hydride / toluene / 0 - 20 °C
With
dmap; diisobutylaluminium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride;
In
tetrahydrofuran; dichloromethane; toluene;
