17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-hydroxymorphinan

Base Information

Chemical Name:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-hydroxymorphinan
CAS No.:1032280-69-5
Molecular Formula:C₃₅H₃₉NO₅
Molecular Weight:553.698
Hs Code.:

Synonyms:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-hydroxymorphinan

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Chemical Property of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-hydroxymorphinan

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Technology Process of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-hydroxymorphinan

There total 1 articles about 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-hydroxymorphinan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 2746-25-0
p-Methoxybenzyl bromide

: 141555-34-2
3-(benzyloxy)-4,5α-epoxy-6β,14-dihydroxy-17-(cyclopropylmethyl)morphinan

: 1032280-69-5
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-hydroxymorphinan

Guidance literature:: 3-(benzyloxy)-4,5α-epoxy-6β,14-dihydroxy-17-(cyclopropylmethyl)morphinan; With sodium hydride; In N,N-dimethyl-formamide; for 0.333333h;

p-Methoxybenzyl bromide; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield: 70.0%

: 598-05-0
di-1-propyl sulfate

: 1032280-69-5
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-hydroxymorphinan

: 1032280-71-9
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-propyloxymorphinan

Guidance literature:: 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-6β-(4-methoxybenzyloxy)-14-hydroxymorphinan; With sodium hydride; In N,N-dimethyl-formamide; for 0.333333h;

di-1-propyl sulfate; In N,N-dimethyl-formamide; at 20 ℃;