Benzamide, 5-bromo-2,3-dimethoxy-N-(2-pyrrolidinylmethyl)-, (S)-

Base Information

Chemical Name:Benzamide, 5-bromo-2,3-dimethoxy-N-(2-pyrrolidinylmethyl)-, (S)-
CAS No.:107188-96-5
Molecular Formula:C₁₄H₁₉BrN₂O₃
Molecular Weight:343.22
Hs Code.:
DSSTox Substance ID:DTXSID201173127

Synonyms:SCHEMBL10355474;DTXSID201173127;Benzamide, 5-bromo-2,3-dimethoxy-N-(2-pyrrolidinylmethyl)-, (S)-;107188-96-5

Suppliers and Price of Benzamide, 5-bromo-2,3-dimethoxy-N-(2-pyrrolidinylmethyl)-, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Benzamide, 5-bromo-2,3-dimethoxy-N-(2-pyrrolidinylmethyl)-, (S)-

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:342.05791
Heavy Atom Count:20
Complexity:330

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)C(=O)NCC2CCCN2)Br
Isomeric SMILES:COC1=CC(=CC(=C1OC)C(=O)NC[C@@H]2CCCN2)Br

Technology Process of Benzamide, 5-bromo-2,3-dimethoxy-N-(2-pyrrolidinylmethyl)-, (S)-

There total 3 articles about Benzamide, 5-bromo-2,3-dimethoxy-N-(2-pyrrolidinylmethyl)-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-Bromo-2,3-dimethoxy-N-((S)-1-trityl-pyrrolidin-2-ylmethyl)-benzamide

: 107188-96-5
(+)-(S)-5-Bromo-2,3-dimethoxy-N-benzamide

Guidance literature:: With hydrogenchloride; In ethanol; for 1h; Yield given; Ambient temperature;
DOI:10.1002/hlca.19900730221

Reference yield:

: 72517-23-8
5-bromo-2,3-dimethoxybenzoic acid

: 107188-96-5
(+)-(S)-5-Bromo-2,3-dimethoxy-N-benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / toluene / 2 h / 50 °C

2: CH₂Cl₂ / 1 h / Ambient temperature

3: conc. HCl / ethanol / 1 h / Ambient temperature

With hydrogenchloride; thionyl chloride; In ethanol; dichloromethane; toluene;
DOI:10.1002/hlca.19900730221

Reference yield:

: 107188-91-0
5-bromo-2,3-dimethoxybenzoic acid chloride

: 107188-96-5
(+)-(S)-5-Bromo-2,3-dimethoxy-N-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂ / 1 h / Ambient temperature

2: conc. HCl / ethanol / 1 h / Ambient temperature

With hydrogenchloride; In ethanol; dichloromethane;
DOI:10.1002/hlca.19900730221