2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol

Base Information

• Chemical Name: 2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol
• CAS No.: 287400-42-4
• Molecular Formula: C₂₃H₃₀O₄Si
• Molecular Weight: 398.574

Synonyms:2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol

Chemical Property of 2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol

There total 1 articles about 2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2R,3S,4R)-3,4-Bis-benzyloxy-2-benzyloxymethyl-5-methyl-3,4-dihydro-2H-pyran → 2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol (287400-42-4)

Guidance literature:

Multi-step reaction with 2 steps

1: Na / liquid ammonia; tetrahydrofuran / 0.28 h / -78 °C

2: imidazole / dimethylformamide

With 1H-imidazole; sodium; In tetrahydrofuran; ammonia; N,N-dimethyl-formamide; 1: debenzylation / 2: silylation;

DOI:10.1021/jo0002801

Reference yield: 97.0%

p-methoxybenzyloxy acetic acid (88920-24-5) + 2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol (287400-42-4) → (4-methoxy-benzyloxy)-acetic acid 2-(tert-butyl-diphenyl-silanyloxymethyl)-4-[(4-methoxy-benzyloxy)-acetoxy]-5-methyl-3,4-dihydro-2H-pyran-3-yl ester (287400-43-5)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide;

DOI:10.1021/jo0002801

Reference yield: 90.0%

(R)-methylbenzyloxyacetic acid (287400-47-9) + 2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol (287400-42-4) → ((R)-1-Phenyl-ethoxy)-acetic acid (2R,3S,4R)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-4-[2-((R)-1-phenyl-ethoxy)-acetoxy]-3,4-dihydro-2H-pyran-3-yl ester (287400-48-0)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide;

DOI:10.1021/jo0002801

Downstream raw materials:

(4-methoxy-benzyloxy)-acetic acid 2-(tert-butyl-diphenyl-silanyloxymethyl)-4-[(4-methoxy-benzyloxy)-acetoxy]-5-methyl-3,4-dihydro-2H-pyran-3-yl ester

((S)-1-Phenyl-ethoxy)-acetic acid (2R,3S,4R)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-4-[2-((S)-1-phenyl-ethoxy)-acetoxy]-3,4-dihydro-2H-pyran-3-yl ester

((R)-1-Phenyl-ethoxy)-acetic acid (2R,3S,4R)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-4-[2-((R)-1-phenyl-ethoxy)-acetoxy]-3,4-dihydro-2H-pyran-3-yl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 287400-42-4 2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-3,4-dihydro-2H-pyran-3,4-diol

Send

Send

Metric Ton KG G Pound L ML

Send

Send