SUCCINIC ACID MONO ISOPROPYL ESTER

Base Information

• Chemical Name: SUCCINIC ACID MONO ISOPROPYL ESTER
• CAS No.: 20279-38-3
• Molecular Formula: C7H12 O4
• Molecular Weight: 160.17
• Hs Code.: 2918990090
• Mol file: 20279-38-3.mol

Synonyms:Butanedioicacid, mono(1-methylethyl) ester (9CI); Succinic acid, isopropyl ester (6CI);Succinic acid, monoisopropyl ester (8CI); Monoisopropyl succinate

Chemical Property of SUCCINIC ACID MONO ISOPROPYL ESTER

Chemical Property:

• PSA: 63.60000
• LogP: 0.80280

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Monoisopropyl Succinate is used in preparation of prodrugs of ketamine for treating or preventing a CNS diseases.

Technology Process of SUCCINIC ACID MONO ISOPROPYL ESTER

There total 2 articles about SUCCINIC ACID MONO ISOPROPYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

2-Methylcyclopentane-1,3-dione (765-69-5) + isopropyl alcohol (67-63-0,8013-70-5) → 3-(isopropoxycarbonyl)propanoic acid (20279-38-3) + diisopropyl succinate (924-88-9)

Guidance literature:

With potassium peroxomonosulfate; at 20 ℃; for 18h;

DOI:10.1021/jo048665x

Reference yield: 31.0%

1,3-cyclopentadione (3859-41-4) + isopropyl alcohol (67-63-0,8013-70-5) → 3-(isopropoxycarbonyl)propanoic acid (20279-38-3) + diisopropyl succinate (924-88-9)

Guidance literature:

With potassium peroxomonosulfate; at 20 ℃; for 18h;

DOI:10.1021/jo048665x

Reference yield:

3-(isopropoxycarbonyl)propanoic acid (20279-38-3) + isopropyl alcohol (67-63-0,8013-70-5) → diisopropyl succinate (924-88-9)

Guidance literature:

3-(isopropoxycarbonyl)propanoic acid; isopropyl alcohol; xylene sulfonic acid catalyst; at 110 ℃;

With potassium hydroxide;

upstream raw materials:

2-Methylcyclopentane-1,3-dione

isopropyl alcohol

1,3-cyclopentadione

Downstream raw materials:

3-{N'-[5-(2,4-Dichloro-6-fluoro-phenoxy)-2-nitro-phenyl]-N'-propyl-hydrazinocarbonyl}-propionic acid isopropyl ester

3-{N'-[2-Nitro-5-(2,4,6-trichloro-phenoxy)-phenyl]-N'-propyl-hydrazinocarbonyl}-propionic acid isopropyl ester

3-{N'-Methyl-N'-[2-nitro-5-(2,4,6-trichloro-phenoxy)-phenyl]-hydrazinocarbonyl}-propionic acid isopropyl ester

3-{N'-[5-(2-Chloro-4-trifluoromethyl-phenoxy)-2-nitro-phenyl]-hydrazinocarbonyl}-propionic acid isopropyl ester

Refernces