{3-[(R)-2-(4-isobutylphenyl)propionylamino]propyl}methylcarbamic acid tert-butyl ester

Base Information

Chemical Name:{3-[(R)-2-(4-isobutylphenyl)propionylamino]propyl}methylcarbamic acid tert-butyl ester
CAS No.:859828-47-0
Molecular Formula:C₂₂H₃₆N₂O₃
Molecular Weight:376.539
Hs Code.:

Synonyms:{3-[(R)-2-(4-isobutylphenyl)propionylamino]propyl}methylcarbamic acid tert-butyl ester

Suppliers and Price of {3-[(R)-2-(4-isobutylphenyl)propionylamino]propyl}methylcarbamic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of {3-[(R)-2-(4-isobutylphenyl)propionylamino]propyl}methylcarbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of {3-[(R)-2-(4-isobutylphenyl)propionylamino]propyl}methylcarbamic acid tert-butyl ester

There total 3 articles about {3-[(R)-2-(4-isobutylphenyl)propionylamino]propyl}methylcarbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 115465-11-7
[3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)propyl]carbamic acid tert-butyl ester

: 859828-47-0
{3-[(R)-2-(4-isobutylphenyl)propionylamino]propyl}methylcarbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH

1.2: hydrazine

2.1: 2.25 g / Et₃N / CH₂Cl₂ / 4 h

With sodium hydride; triethylamine; In dichloromethane;
DOI:10.1021/jm049082i

Reference yield:

: 51146-57-7,58560-75-1
(R)-ibuprofene

: 859828-47-0
{3-[(R)-2-(4-isobutylphenyl)propionylamino]propyl}methylcarbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 3 h / Heating

2: 2.25 g / Et₃N / CH₂Cl₂ / 4 h

With thionyl chloride; triethylamine; In dichloromethane;
DOI:10.1021/jm049082i