6-{[α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartyl(β-benzyl ester)]amino}-7-methyl-3-benzyl-1-octen-5-one

Base Information

• Chemical Name: 6-{[α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartyl(β-benzyl ester)]amino}-7-methyl-3-benzyl-1-octen-5-one
• CAS No.: 191930-79-7
• Molecular Formula: C₅₅H₆₉N₉O₁₂
• Molecular Weight: 1048.21
• Mol file: 191930-79-7.mol

Synonyms:6-{[α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartyl(β-benzyl ester)]amino}-7-methyl-3-benzyl-1-octen-5-one

Chemical Property of 6-{[α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartyl(β-benzyl ester)]amino}-7-methyl-3-benzyl-1-octen-5-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-{[α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartyl(β-benzyl ester)]amino}-7-methyl-3-benzyl-1-octen-5-one

There total 4 articles about 6-{[α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartyl(β-benzyl ester)]amino}-7-methyl-3-benzyl-1-octen-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartic acid β-benzyl ester (72210-37-8) → 6-{[α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartyl(β-benzyl ester)]amino}-7-methyl-3-benzyl-1-octen-5-one (191930-79-7)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC / 2.5 h

2: Et₃N / tetrahydrofuran / 3 h

With triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran;

DOI:10.1021/jm950803a

Reference yield:

α,ε-dicarbobenzoyloxynitroarginyllysine (107304-39-2) → 6-{[α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartyl(β-benzyl ester)]amino}-7-methyl-3-benzyl-1-octen-5-one (191930-79-7)

Guidance literature:

Multi-step reaction with 5 steps

1: DCC / tetrahydrofuran / 18 h / Ambient temperature

2: Et₃N / tetrahydrofuran / 4 h

3: 87 percent / TFA, anisole / 0.5 h / 0 °C

4: DCC / 2.5 h

5: Et₃N / tetrahydrofuran / 3 h

With methoxybenzene; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran;

DOI:10.1021/jm950803a

Reference yield:

C32H40N8O11 → 6-{[α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartyl(β-benzyl ester)]amino}-7-methyl-3-benzyl-1-octen-5-one (191930-79-7)

Guidance literature:

Multi-step reaction with 4 steps

1: Et₃N / tetrahydrofuran / 4 h

2: 87 percent / TFA, anisole / 0.5 h / 0 °C

3: DCC / 2.5 h

4: Et₃N / tetrahydrofuran / 3 h

With methoxybenzene; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran;

DOI:10.1021/jm950803a

upstream raw materials:

α-(carbobenzyloxy)nitroarginyl-ε-(carbobenzyloxy)lysylaspartic acid β-benzyl ester

α,ε-dicarbobenzoyloxynitroarginyllysine

C₅₂H₅₈N₈O₁₂