METHYL-6-O-TRIPHENYLMETHYL-ALPHA-D-MANNOPYRANOSIDE

Base Information

• Chemical Name: METHYL-6-O-TRIPHENYLMETHYL-ALPHA-D-MANNOPYRANOSIDE
• CAS No.: 20231-36-1
• Molecular Formula: C26H28 O6
• Molecular Weight: 436.505
• Hs Code.: 2932999099
• Mol file: 20231-36-1.mol

Synonyms:Mannopyranoside,methyl 6-O-trityl-, a-D- (8CI); Methyl 5-O-trityl-a-D-mannopyranoside; Methyl 6-O-trityl-a-D-mannopyranoside

Chemical Property of METHYL-6-O-TRIPHENYLMETHYL-ALPHA-D-MANNOPYRANOSIDE

Chemical Property:

• Boiling Point: 593.3±50.0 °C(Predicted)
• PKA: 12.89±0.70(Predicted)
• PSA: 88.38000
• Density: 1.30±0.1 g/cm3(Predicted)
• LogP: 2.44910

Purity/Quality:

97% ^*data from raw suppliers

METHYL-6-O-TRIPHENYLMETHYL-ALPHA-D-MANNOPYRANOSIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL-6-O-TRIPHENYLMETHYL-ALPHA-D-MANNOPYRANOSIDE

There total 33 articles about METHYL-6-O-TRIPHENYLMETHYL-ALPHA-D-MANNOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

trityl chloride (76-83-5) + (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol (617-04-9) → methyl 6-O-trityl-α-D-mannopyranoside (20231-36-1)

Guidance literature:

With pyridine; at 100 ℃; for 0.5h;

Reference yield: 96.0%

trityl chloride (76-83-5) + methyl beta-D-galactopyranoside (1824-94-8) → methyl 6-O-triphenylmethyl-β-D-galactopyranoside (18311-26-7,20231-36-1,35780-80-4,35920-83-3,51785-34-3,67412-01-5,68027-25-8,73111-51-0)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In dichloromethane; at 30 ℃; for 8h; regioselective reaction;

DOI:10.1080/00397910802656067

Reference yield: 90.0%

trityl chloride (76-83-5) + methyl α-D-galactopyranoside (3396-99-4) → methyl 6-O-triphenylmethyl-α-D-galactopyranoside (18311-26-7,20231-36-1,35780-80-4,35920-83-3,51785-34-3,67412-01-5,68027-25-8,73111-51-0)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1021/ol301779e

upstream raw materials:

trityl chloride

methyl α-D-galactopyranoside

methyl 3,6-di-O-trityl-α-D-galactopyranoside

(2R,3R,4S,5R,6S)-6-Methoxy-5-trityloxy-2-trityloxymethyl-tetrahydro-pyran-3,4-diol

Downstream raw materials:

methyl 2,3,4-tri-O-acetyl-6-O-trityl-α-D-galactopyranoside

methyl 2,3,4-tri-O-benzyl-6-O-triphenylmethyl-β-D-galactopyranoside

methyl 3,4-O-isopropylidene-6-O-trityl-β-D-galactopyranoside

(2R,3R,4S,5R,6R)-2-Hydroxymethyl-6-((2R,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-ylmethoxy)-tetrahydro-pyran-3,4,5-triol