N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-hydroxyethyl)-2-benzyloxyphenyl]formamide

Base Information

• Chemical Name: N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-hydroxyethyl)-2-benzyloxyphenyl]formamide
• CAS No.: 849540-71-2
• Molecular Formula: C₃₂H₃₆N₄O₃
• Molecular Weight: 524.663

Synonyms:N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-hydroxyethyl)-2-benzyloxyphenyl]formamide

Chemical Property of N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-hydroxyethyl)-2-benzyloxyphenyl]formamide

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Technology Process of N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-hydroxyethyl)-2-benzyloxyphenyl]formamide

There total 1 articles about N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-hydroxyethyl)-2-benzyloxyphenyl]formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-(tert-butyldimethylsilanyloxy)ethyl)-2-benzyloxyphenyl]formamide (849540-59-6) → N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-hydroxyethyl)-2-benzyloxyphenyl]formamide (849540-71-2)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In tetrahydrofuran; for 8h;

Reference yield:

N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-hydroxyethyl)-2-benzyloxyphenyl]formamide (849540-71-2) → N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenyl-ethylamino)phenyl]ethylamino}-1-hydroxyethyl)-2-hydroxyphenyl]-formamide

Guidance literature:

With hydrogen; acetic acid; 20% Pd(OH)2 on carbon; In ethanol; for 20h; under 760.051 Torr;

upstream raw materials:

N-[5-((R)-2-{2-[4-((S)-2-amino-2-phenylethylamino)phenyl]-ethylamino}-1-(tert-butyldimethylsilanyloxy)ethyl)-2-benzyloxyphenyl]formamide

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