1-methyl-2-(2,6-dichloro-4-methoxy-phenyl)-4-chloro-6-methoxy-indole

Base Information

• Chemical Name: 1-methyl-2-(2,6-dichloro-4-methoxy-phenyl)-4-chloro-6-methoxy-indole
• CAS No.: 83363-99-9
• Molecular Formula: C₁₇H₁₄Cl₃NO₂
• Molecular Weight: 370.663
• Mol file: 83363-99-9.mol

Synonyms:1-methyl-2-(2,6-dichloro-4-methoxy-phenyl)-4-chloro-6-methoxy-indole

Chemical Property of 1-methyl-2-(2,6-dichloro-4-methoxy-phenyl)-4-chloro-6-methoxy-indole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-methyl-2-(2,6-dichloro-4-methoxy-phenyl)-4-chloro-6-methoxy-indole

There total 2 articles about 1-methyl-2-(2,6-dichloro-4-methoxy-phenyl)-4-chloro-6-methoxy-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-Bis-(2,6-dichloro-4-methoxy-phenyl)-N,N'-dimethyl-ethane-1,2-diamine (82783-97-9,82784-00-7) → 1-methyl-2-(2,6-dichloro-4-methoxy-phenyl)-4-chloro-6-methoxy-indole (83363-99-9)

Guidance literature:

With methylamine hydrochloride; at 215 ℃; for 0.25h;

DOI:10.1021/jm00355a024

Reference yield:

→ 1-methyl-2-(2,6-dichloro-4-methoxy-phenyl)-4-chloro-6-methoxy-indole (83363-99-9)

Guidance literature:

Reference yield:

1-methyl-2-(2,6-dichloro-4-methoxy-phenyl)-4-chloro-6-methoxy-indole (83363-99-9) → 1-Methyl-2-(2,6-dichloro-4-hydroxyphenyl)-4-chloro-6-hydroxy-indole (83364-02-7)

Guidance literature:

With boron tribromide; In dichloromethane; at -60 - 20 ℃; for 15.5h;

DOI:10.1021/jm00355a024

upstream raw materials:

1,2-Bis-(2,6-dichloro-4-methoxy-phenyl)-N,N'-dimethyl-ethane-1,2-diamine

Downstream raw materials:

1-Methyl-2-(2,6-dichloro-4-hydroxyphenyl)-4-chloro-6-hydroxy-indole