N-(3-bromo-4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzenecarboximidamide

Base Information

• Chemical Name: N-(3-bromo-4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzenecarboximidamide
• CAS No.: 1332847-62-7
• Molecular Formula: C₂₁H₁₉BrN₂O₃S
• Molecular Weight: 459.363
• Mol file: 1332847-62-7.mol

Synonyms:N-(3-bromo-4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzenecarboximidamide

Chemical Property of N-(3-bromo-4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzenecarboximidamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3-bromo-4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzenecarboximidamide

There total 3 articles about N-(3-bromo-4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzenecarboximidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

N-(2,5-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)-N'-(phenylsulfonyl)benzenecarboximidamide (461672-48-0) → N-(3-bromo-4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzenecarboximidamide (1332847-62-7)

Guidance literature:

With hydrogen bromide; In water; acetic acid; at 50 - 60 ℃;

DOI:10.1134/S1070428011070116

Reference yield:

N-(4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzimidamide (461672-41-3) → N-(3-bromo-4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzenecarboximidamide (1332847-62-7)

Guidance literature:

Multi-step reaction with 2 steps

1: lead(IV) tetraacetate / acetic acid

2: hydrogen bromide / water; acetic acid / 50 - 60 °C

With hydrogen bromide; lead(IV) tetraacetate; In water; acetic acid;

DOI:10.1134/S1070428011070116

Reference yield:

2,5-dimethyl-4-amino phenol (3096-71-7) → N-(3-bromo-4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzenecarboximidamide (1332847-62-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate / acetic acid; N,N-dimethyl-formamide

2: bromine / chloroform / 24 h / 40 - 50 °C

With bromine; sodium acetate; In chloroform; acetic acid; N,N-dimethyl-formamide;

DOI:10.1134/S107042801207007X

upstream raw materials:

N-(4-hydroxy-2,5-dimethylphenyl)-N'-(phenylsulfonyl)benzimidamide

N-(2,5-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)-N'-(phenylsulfonyl)benzenecarboximidamide

2,5-dimethyl-4-amino phenol

Downstream raw materials:

N-(3-bromo-2,5-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)-N'-(phenylsulfonyl)benzenecarboximidamide