(2E)-3-(4-Chlorophenyl)-N-[(1S)-2-oxo-2-[[2-oxo-2-[4-(3,3,3-trifluoropropyl)-1-piperazinyl]ethyl]amino]-1-(pyridin-2-ylmethyl)-ethyl]-2-propenamide

Base Information

Chemical Name:(2E)-3-(4-Chlorophenyl)-N-[(1S)-2-oxo-2-[[2-oxo-2-[4-(3,3,3-trifluoropropyl)-1-piperazinyl]ethyl]amino]-1-(pyridin-2-ylmethyl)-ethyl]-2-propenamide
CAS No.:337530-58-2
Molecular Formula:C₂₆H₂₉ClF₃N₅O₃
Molecular Weight:551.996
Hs Code.:

Synonyms:(2E)-3-(4-Chlorophenyl)-N-[(1S)-2-oxo-2-[[2-oxo-2-[4-(3,3,3-trifluoropropyl)-1-piperazinyl]ethyl]amino]-1-(pyridin-2-ylmethyl)-ethyl]-2-propenamide

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Chemical Property of (2E)-3-(4-Chlorophenyl)-N-[(1S)-2-oxo-2-[[2-oxo-2-[4-(3,3,3-trifluoropropyl)-1-piperazinyl]ethyl]amino]-1-(pyridin-2-ylmethyl)-ethyl]-2-propenamide

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Technology Process of (2E)-3-(4-Chlorophenyl)-N-[(1S)-2-oxo-2-[[2-oxo-2-[4-(3,3,3-trifluoropropyl)-1-piperazinyl]ethyl]amino]-1-(pyridin-2-ylmethyl)-ethyl]-2-propenamide

There total 1 articles about (2E)-3-(4-Chlorophenyl)-N-[(1S)-2-oxo-2-[[2-oxo-2-[4-(3,3,3-trifluoropropyl)-1-piperazinyl]ethyl]amino]-1-(pyridin-2-ylmethyl)-ethyl]-2-propenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 337530-31-1
[[(2S)-2-[[(2E)-3-(4-chlorophenyl)-2-propenoyl]amino]-3-(pyridin-2-yl)propanoyl]amino]acetic acid

: 1-(3,3,3-trifluoropropyl)piperazine dihydrochloride

: 337530-58-2
(2E)-3-(4-Chlorophenyl)-N-[(1S)-2-oxo-2-[[2-oxo-2-[4-(3,3,3-trifluoropropyl)-1-piperazinyl]ethyl]amino]-1-(pyridin-2-ylmethyl)-ethyl]-2-propenamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 10 - 20 ℃; for 2.83333h;