Technology Process of Nb-benzylalstonerine
There total 3 articles about Nb-benzylalstonerine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
methanol;
at 20 ℃;
for 12h;
DOI:10.1021/jo000126e
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 85 percent / BH3 / tetrahydrofuran / 32 h / 0 °C
2: 80 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / -78 - 20 °C
3: 90 percent / 2N NaOH / methanol / 12 h / 20 °C
With
sodium hydroxide; oxalyl dichloride; borane; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane;
1: hydration / 2: Oxidation / 3: Elimination;
DOI:10.1021/jo000126e
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 80 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / -78 - 20 °C
2: 90 percent / 2N NaOH / methanol / 12 h / 20 °C
With
sodium hydroxide; oxalyl dichloride; dimethyl sulfoxide; triethylamine;
In
methanol; dichloromethane;
1: Oxidation / 2: Elimination;
DOI:10.1021/jo000126e
