5(S)-<<(tert-Butyldiphenylsilyl)oxy>methyl>-4(R)-ethyldihydro-2(3H)-furanone

Base Information

• Chemical Name: 5(S)-<<(tert-Butyldiphenylsilyl)oxy>methyl>-4(R)-ethyldihydro-2(3H)-furanone
• CAS No.: 121687-49-8
• Molecular Formula: C₂₃H₃₀O₃Si
• Molecular Weight: 382.575

Synonyms:5(S)-<<(tert-Butyldiphenylsilyl)oxy>methyl>-4(R)-ethyldihydro-2(3H)-furanone

Chemical Property of 5(S)-<<(tert-Butyldiphenylsilyl)oxy>methyl>-4(R)-ethyldihydro-2(3H)-furanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5(S)-<<(tert-Butyldiphenylsilyl)oxy>methyl>-4(R)-ethyldihydro-2(3H)-furanone

There total 18 articles about 5(S)-<<(tert-Butyldiphenylsilyl)oxy>methyl>-4(R)-ethyldihydro-2(3H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

ethylmagnesium bromide (925-90-6) + (5S)-5-(tert-butyldiphenylsiloxymethyl)-2(5H)-furanone (99315-76-1) → 3-C-ethyl-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-D-erythro-pentono-1,4-lactone (121687-49-8)

Guidance literature:

With copper(I) thiophenolate; In tetrahydrofuran; at -30 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1002/ejoc.201000587

Reference yield: 67.0%

(5S)-5-(tert-butyldiphenylsiloxymethyl)-2(5H)-furanone (99315-76-1) → 3-C-ethyl-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-D-erythro-pentono-1,4-lactone (121687-49-8)

Guidance literature:

In tetrahydrofuran; at -15 - -10 ℃; for 0.5h;

DOI:10.1016/0008-6215(88)84079-5

Reference yield: 64.0%

4-Ethyl-5(R)-<<(tert-butyldiphenylsilyl)oxy>methyl>-2(3H)-furanone (137870-97-4) → 5(S)-<<(tert-Butyldiphenylsilyl)oxy>methyl>-4(R)-ethyldihydro-2(3H)-furanone (121687-49-8)

Guidance literature:

With copper(I) hydride; iso-butanol; In tetrahydrofuran; 1) -78 deg C, 1 h, 2) -20 deg C, 1h;

DOI:10.1021/jo00023a017

upstream raw materials:

4-Ethyl-5(R)-<<(tert-butyldiphenylsilyl)oxy>methyl>-2(3H)-furanone

ethyl (Z)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate

ethyl (E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate

1-(2,2-Dimethyl-[1,3]dioxolan-4-yl)-propan-1-one

Downstream raw materials:

5-<(tert-Butyldiphenylsilyl)oxy>-2(R),4(S)-dihydroxy-3(R)-ethylpentane

(3R,4R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-ethyl-2,3-dimethyl-tetrahydro-furan-2-ol

(3R,4R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-ethyl-2,3-dimethyl-tetrahydro-furan-2-yl-hydroperoxide

Ethaneperoxoic acid (3R,4R,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-4-ethyl-2,3-dimethyl-tetrahydro-furan-2-yl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 121687-49-8 5(S)-<<(tert-Butyldiphenylsilyl)oxy>methyl>-4(R)-ethyldihydro-2(3H)-furanone

Send

Send

Metric Ton KG G Pound L ML

Send

Send