N-(4-nitrophenyl)-N',N'-(3-oxapentamethylene)-5-norbornene-2-carboxamidine

Base Information

• Chemical Name: N-(4-nitrophenyl)-N',N'-(3-oxapentamethylene)-5-norbornene-2-carboxamidine
• CAS No.: 97325-91-2
• Molecular Formula: C₁₈H₂₁N₃O₃
• Molecular Weight: 327.383
• Mol file: 97325-91-2.mol

Synonyms:N-(4-nitrophenyl)-N',N'-(3-oxapentamethylene)-5-norbornene-2-carboxamidine

Chemical Property of N-(4-nitrophenyl)-N',N'-(3-oxapentamethylene)-5-norbornene-2-carboxamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-nitrophenyl)-N',N'-(3-oxapentamethylene)-5-norbornene-2-carboxamidine

There total 5 articles about N-(4-nitrophenyl)-N',N'-(3-oxapentamethylene)-5-norbornene-2-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

5'-morpholino-1'-(4-nitrophenyl)-4',5'-dihydro-spirohept-2-ene<5.4'>-1',2',3'-triazole> → N-(4-nitrophenyl)-N',N'-(3-oxapentamethylene)-5-norbornene-2-carboxamidine (97325-91-2)

Guidance literature:

In xylene; for 0.5h; Heating;

DOI:10.1016/0040-4020(84)85082-6

Reference yield:

4-nitrophenyl azide (1516-60-5) → N-(4-nitrophenyl)-N',N'-(3-oxapentamethylene)-5-norbornene-2-carboxamidine (97325-91-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / benzene / 3.5 h / Ambient temperature

2: 58 percent / xylene / 0.5 h / Heating

In xylene; benzene;

DOI:10.1016/0040-4020(84)85082-6

Reference yield:

4,5-Dihydro-4-methylene-5-morpholino-1-(4-nitrophenyl)-ν-triazole (74073-15-7) → N-(4-nitrophenyl)-N',N'-(3-oxapentamethylene)-5-norbornene-2-carboxamidine (97325-91-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 25 percent / tetrahydrofuran / 72 h / 0 - 5 °C

2: 58 percent / xylene / 0.5 h / Heating

In tetrahydrofuran; xylene;

DOI:10.1016/0040-4020(84)85082-6

upstream raw materials:

4-nitrophenyl azide

4,5-Dihydro-4-methylene-5-morpholino-1-(4-nitrophenyl)-ν-triazole

cyclopenta-1,3-diene

5-morpholino-methylene-2-norbornene

Downstream raw materials:

N-(4-nitrophenyl)-norbornene-2-carboxamide