6-(4-cyanophenyl)-3-fluoro-2,4-dimethyl-2-trimethylsilylmethyl-5,6-dihydro-2H-pyran

Base Information

• Chemical Name: 6-(4-cyanophenyl)-3-fluoro-2,4-dimethyl-2-trimethylsilylmethyl-5,6-dihydro-2H-pyran
• CAS No.: 1266680-87-8
• Molecular Formula: C₁₈H₂₄FNOSi
• Molecular Weight: 317.479

Synonyms:6-(4-cyanophenyl)-3-fluoro-2,4-dimethyl-2-trimethylsilylmethyl-5,6-dihydro-2H-pyran

Chemical Property of 6-(4-cyanophenyl)-3-fluoro-2,4-dimethyl-2-trimethylsilylmethyl-5,6-dihydro-2H-pyran

Chemical Property:

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Technology Process of 6-(4-cyanophenyl)-3-fluoro-2,4-dimethyl-2-trimethylsilylmethyl-5,6-dihydro-2H-pyran

There total 1 articles about 6-(4-cyanophenyl)-3-fluoro-2,4-dimethyl-2-trimethylsilylmethyl-5,6-dihydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

3-fluoro-2,4-dimethyl-5-trimethylsilylpenta-1,3-diene + 4-cyanobenzaldehyde (105-07-7) → 6-(4-cyanophenyl)-3-fluoro-2,4-dimethyl-2-trimethylsilylmethyl-5,6-dihydro-2H-pyran (1266680-87-8)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -78 - 25 ℃; for 19h; Inert atmosphere;

DOI:10.1016/j.tetlet.2010.12.005

upstream raw materials:

4-cyanobenzaldehyde

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